Drug discovery > Pre-Clinical Development Products & Reviews

The CellTiter-Glo® Luminescent Cell Viability Assay(a,b) is a homogeneous method of determining the number of viable cells in culture based on quantitation of the ATP present, an indicator of metabolically active cells. The CellTiter-Glo® Assay is designed for use with multiwell formats, making it ideal for automated high-throughput screening (HTS), cell proliferation and cytotoxicity assays. The homogeneous assay procedure in…

The CellTiter-Glo® 2.0 Assay provides a homogeneous method for determining the number of viable cells in culture by measuring the amount of ATP present, which indicates the presence of metabolically active cells. The CellTiter-Glo® 2.0 Assay is based on the original CellTiter-Glo® Assay chemistry but with improved storage convenience for easy implementation. The CellTiter-Glo® 2.0 Assay is provided as a single, ready-to-use re…

The Lactate-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of L-lactate in biological samples. Lactate is produced by glycolysis, a major metabolic pathway responsible for glucose homeostasis and energy production (1,2). Once considered merely a byproduct of glycolysis, lactate is now considered an important regulatory molecule of intermediate metabolism involved in cancer development, diabet…

A Fluorometric Method for Estimating the Number of Nonviable Cells Present in Multiwell Plates

A Simple, Non-Radioactive Assay to Measure Glucose Uptake Inside Cells

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

The Caspase-Glo ® 3/7 Assay System is  a highly sensitive caspase activity assay for use in plate-reader assays.

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

The GSH-Glo™ Glutathione Assay is a luminescence-based assay for the detection and quantification of glutathione (GSH). The assay is based on the conversion of a luciferin derivative into luciferin in the presence of glutathione, catalyzed by glutathione S-transferase (GST). The signal generated in a coupled reaction with firefly luciferase is proportional to the amount of glutathione present in the sample. Luminescence is gen…

IRDye and VRDye secondary antibodies are highly cross-adsorbed, making them suitable for multi-color detection. IRDye secondary antibodies have been optimized for use with the Odyssey® family of imaging systems and can be used on instruments with similar excitation and emission filters.

The Pearl Trilogy Small Animal Imaging System is a small animal in vivo imaging system that offers bioluminescence detection and dual-channel near-infrared fluorescent detection.

The Indus Doppler Flow Velocity System is a high-frequency, real-time pulsed Doppler measurement device with integrated data analysis software designed for measuring cardiovascular function in small animals.

Anti-Mullerian Hormone (AMH) immunoassay is a useful research tool in reproductive endocrinology studies related to primary ovarian insufficiency, oncofertility, gonadotoxicity, menopause, premature ovarian aging, PCOS, neonatal gender determination, Cryptorchidism, Testicular (Leydig/Sertoli cell) function.

The Inhibin A enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of dimeric inhibin A in human serum and plasma. It is intended for in vitro diagnostic use as an aid in the diagnosis and monitoring of various hormonal reproductive disorders.

Elevated levels of activin A have been implicated in colorectal and breast cancers in post-menopausal women. FST and FSTL3 are natural binding proteins of activin A. Exogenous FST/FSTL3 do not interfere with activin A determinations. Activin signaling also has been studied as an emerging target for therapeutics.

Inhibin B is a useful research tool in Reproductive Endocrinology studies related to ovarian function assessment, spermatogenesis and testicular function, and oocyte quality.

The Ansh Labs' Bovine Anti-Müllerian hormone (AMH) enzyme-linked immunosorbent assay (ELISA) kit is the only AMH assay designed specifically for use in cattle.  Numerous publications, collaborations, dissertations, and similar studies have used the Ansh Labs' Bovine AMH ELISA asasy in countless breeds to include Jersey, Hereford, Holstein, Angus, Red Angus, Black Angus, Brahman, Gyr, Nelore, Murrah, Beefmaster, Brangus, Holste…

The MenoCheck® picoAMH ELISA is FDA cleared for in vitro diagnostic use as an aid in the determination of menopausal status in women between 42 and 62 years of age. This is the only AMH test with the sensitivity to quantify declining AMH concentrations in women who are entering their menopausal transition.

Live-cell analysis system

Fast, accurate, and automated brightfield and fluorescent cell counting

Lux3 BR is a small brightfield live-cell imager, equipped with a high-quality 6.4 MP CMOS camera. It is designed to work inside a standard cell culture incubator without disturbing temperature, airflow, and optimum culture conditions. Detailed brightfield images can be captured using the new device. In both x- and y-direction, 2072 pixels combined with 1.45 mm field of view provide a resolution of 0.7 µm/pixel. 

High-throughput live-cell analysis system

The iNSiGHT DXA system is an in vivo Dual Energy X-Ray Absorptiometry (DXA/DEXA) technology for preclinical research. This fully shielded X-ray cabinet is suitable for small animal DXA applications – mice, rats, and animals of similar size (up to 5kg). Efficient body composition measurements allow for fast scan times of 25 seconds. Combined with its low-dose radiation, it’s ideal for longitudinal studies.

The Indus Rodent Surgical Monitor+ is an advanced, integrated surgical warming and vital signs monitoring solution for preclinical research in mice, rats and other small animals. The system provides detailed information, in real time, regarding subject body temperature, ECG, heart rate, pressure and respiration. 

PIPETMAX® is an automated pipetting solution for the efficient processing of high-throughput biological assays. It will help you to improve on the accuracy, reproducibility, and consistency among all samples processed. Unlike traditional automation platforms, PIPETMAX comes in a benchtop size that easily fits into any lab.