Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Costar® Spin-X® Centrifuge Tube Filters, 0.22 µm Pore CA Membrane, Nonsterile, 100/Case

Corning Life Sciences

These Costar® Spin-X® centrifuge tube filters have a 0.22 µm pore CA membrane-containing filter unit within a 500 µL capacity polypropylene microcentrifuge tube. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding Ideal for removing bacteria, particles, or cells from liquids, HPLC sample preparation and DNA removal from agarose or acrylamide gels. Nonsterile and certified nonpyrogenic and DNase-…

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DNASIS

Hitachi Software Engineering Europe S.A.

DNASIS - The Most Comprehensive Software Package for Sequence Analysis. All you expect from gene analysis programs is available in DNASIS. In fact, sequence analysis customers have used versions of DNASIS for over 10 years. Hitachi DNASIS has been proven on the job by scientists worldwide to be quick, accurate and reliable. Features of DNASIS include:Comprehensive : an exhaustive list of highly developed sequence analysis…

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Sorcerer UDS for Unscheduled DNA Synthesis

Perceptive Instruments

Sorcerer UDS provides flexible approach to the UDS assay based upon our Sorcerer automatic image analysis system. The system is a fully validated suite of software for UDS compliant with Good Laboratory Practice and FDA 21 CFR Part 11, consisting of a series of modules for creating studies, randomisation, slide scoring, data saving and production of experimental summaries. Interactive automated scoring with calculation of n…

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Corning® 150 mL Bottle Top Vacuum Filter, 0.45 µm Pore 13.6cm² CA Membrane, Fits 45 mm Diameter Necks, Sterile, 48/Case

Corning Life Sciences

Fits plastic or glass media bottles with 45mm neck sizes. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding and are good for filtering cell culture media. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy produ…

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Corning® 500 mL Bottle Top Vacuum Filter, 0.2 µm Pore 33.2cm² Nylon Membrane, Fits 45 mm Diameter Necks, Sterile, 12/Case

Corning Life Sciences

Fits plastic or glass media bottles with 45mm neck sizes. Nylon (NY) membranes are naturally hydrophilic, surfactant-free and offer the lowest extractables. Angled hose connector simplifies vacuum line attachment. Individually packaged, sterile and certified nonpyrogenic. Each system has the membrane material and pore size printed on the unit and is color-coded by membrane type for easy product identification. Expiratio…

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Table Top Laboratory Animal Anesthesia System V1

KF Technology Srl

One dial setting delivers a consistent and safe anesthetic level. Manuals include a "cookbook" protocol which can easily be adapted to your facility's SOP. All waste gases are scavenged for easy evacuation. Breathing circuits allow flat, prone or supine positions with head access. Suitable for mouse, rat, hamster, gerbil, guinea pig, ferret, rabbit, cat, dog or small swine.Positive sealing gasket on induction chambers minimize…

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Bioscan BioFLECT™ 400

Bioscan Inc.

The new Bioscan BioFLECT 400 is the first in vivo optical imaging system offering true 360° fluorescence tomography. BioFLECT uses the photon emission data acquired from 360° and a state-of-the-art 3D reconstruction engine to quantitatively reconstruct the 3D spatial distribution of fluorescent probes in live animals. This approach yields superior, consistent resolution, sensitivity and quantitation throughout the subject. The…

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Tube Auditor™

Brooks Life Sciences

The Tube Auditor™ measures sample volumes and detects precipitate using high-speed vision technology. It gives confidence in the quality of your samples (at both collection and output) and helps reduce downstream costs and waste, which can arise from empty wells and precipitated samples. Applications include Compound Management, High Throughput Screening and Biobanking. 

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EXP® Trap Columns

Optimize Technologies, Inc.

The patent-pending EXP® Trap Column is rated for use at 20,000+ psi (1,400+ bar). This unique design connects directly to any injection valve (with 10-32 threads) or in-line with 1/16” stainless tubing for unparalleled convenience and efficiency. The EXP® Cartridge System enables chemists to quickly remove detergents or salts which can affect the ionization process in MS work. This trapping technique can concentrate the sampl…

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EXP® Stem Trap

Optimize Technologies, Inc.

The entire EXP® Stem Trap and reusable holder are only slightly larger than a standard HPLC fitting. Its slim architecture allows it to easily fit into crowded instrument compartments or to connect directly to tightly-spaced injection ports. When tightened by hand, the EXP® Stem Trap seals to 8,700+ psi. All configurations incorporate wrench-flats to enable flawless sealing to 20,000+ psi (1,400+ bar). The unique packed floati…

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EXP® Stem Filter

Optimize Technologies, Inc.

The EXP® Stem Filter features a choice of frit porosities integrated with our patented auto-adjusting stem for repeated ZDV connections with any 10-32 port. The entire filter stem and reusable holder are only slightly larger than a standard HPLC fitting. This slim architecture allows it to easily fit into crowded instrument compartments, tightly spaced injection ports, and anywhere else you need an extra level of protection ag…

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EXP® Nano Trap

Optimize Technologies, Inc.

The EXP® Nano Trap System is designed to remove detergents or salts which can affect the ionization process in MS work rated for routine use up to 20,000 psi.The new nano-scale traps are available in two formats – EXP® Nano Trap and EXP® Nano Trap HR. Both formats are available in 10 or 20 mm lengths and in a variety of bed volumes ranging from 0.25µL - 4.0µL. The EXP® Nano Trap follows a traditional trap column format, design…

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OPTI-SOLV® Solvent Reservoir Filter

Optimize Technologies, Inc.

OPTI-SOLV® Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing your analysis. While the availability of HPLC-grade solvents diminishes the need for pre-filtering, it is still imperative that a filtration device be installed in the reservoir. Placing a filter in the reservoir is an economical way to filter particles that may result from buffer sal…

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OPTI-SOLV® Biocompatible Solvent Reservoir Filter

Optimize Technologies, Inc.

A solid PTFE body keeps OPTI-SOLV® filter at the base of the bottle where a bottom-mounted titanium frit provides unrestricted solvent access. As always, Optimize makes installation as simple as possible - no tools or fittings required and includes 5 feet of pre-installed PTFE tubing. OPTI-SOLV Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing…

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OPTI-SOLV® In-Line Hand-Tight Filter System

Optimize Technologies, Inc.

The user-friendly Hand-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Placeme…

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OPTI-SOLV® In-Line Wrench-Tight Filter

Optimize Technologies, Inc.

The user-friendly Wrench-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Place…

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OPTI-LYNX™ Quick Connect Trap Columns

Optimize Technologies, Inc.

The OPTI-LYNX™ Quick Connect Trap Columns allow you to quick-connect to any 10-32 valve/port for trapping or analytical column for pre-column filtration. With OPTI-LYNX™, accessing and changing the insert takes only a quarter turn. Replace traps, filters or change configurations in seconds, without tools. OPTI-LYNX™ traps and filters (ordered separately) come in several bed volume/ diameter/ porosity combinations, allowing you…

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Cellwriter 240

BioDot Inc.

Features:Automated Cell DroppingAutomated Probe/DAPI DispensingIntegrated HybridizationImprove Metaphase Spread QualityPerform Up To 8 Assays On One SlideReduce Reagent CostsRemove The Need For Rubber Cement24 Slide Processing Capability

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Pippin Link Group Controller

Sage Science

The Pippin Link Group Control is the best way to reproducibly provide the highest quality size-selected DNA in high-throughput. It provides hardware and software for running up to eight Pippin Instruments from a laptop PC. Three linked-Pippins can produce up to 96 size selections in one day.

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WHEATON® Integrated Biobanking System

WHEATON

WHEATON BioBanking Solutions is a comprehensive offering of high quality products and customized services for your cryogenic needs.Whether you require the storage of irreplaceable samples in glass cryogenic ampules or plastic cryogenic vials, bar coding options for sample traceablity or for color coded storage and freezer boxes, WHEATON provides you with the tools that make your job easier and more efficient while having the c…

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Soxtherm 416

Lab Synergy

Gerhardt has created a complete line of Soxtherm models, creating the ideal opportunity to have a state of the art lab for Extraction systems. One of the most impressive units in the line is the Soxtherm 416, capable of six extraction places capable of holding both small and large beakers. The unit is capable of nearly all analytical areas in fat determination and sample preparation specifically: milk, cereal, meat, oil, fruit…

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Rapid Extraction System (RES)

CambTEK

The CambTEK Rapid Extraction System – A new approach to automated sample preparation of solid dosage forms for improved quality of data and productivity. CambTEK's Rapid Extraction System (RES) delivers a step-change in performance compared with the existing methods, and is achieved using robust technologies and an intelligent consumable. Utilizing non-invasive turbulent flow with the option of ultasonics the RES delivers many…

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Cell Organelle Toolbox

Chromotek GmbH

Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…

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