Drug discovery > Pre-Clinical Development Products & Reviews

2-Amino-2-(hydroxymethyl)-1,3-propanediol

Functions as a coenzyme of a large number of oxidoreductases

IRDye® Click Chemistry reagents (DBCO, Alkyne, and Azide) offer convenient, versatile and reliable methods for biomolecule labeling. With a variety of in vitro and in vivo applications, from biomarker isolation to assay development.

Extending the reach and value of non-destructive nanoscale imaging

LaserFIB Workflow - Enhance Your in situ Studies.

CN Bio supports non-alcoholic steatohepatitis (NASH) therapeutic development via fast-track NASH Contract Research Services. NASH Services enable you to gain instant access to CN Bio’s expertise and one of the most advanced human in vitro models available. Submit lead candidates for screening and receive human translatable data for insightful preclinical candidate prioritization, clinical trial design and optimization.

CN Bio supports R&D efforts via fast-track Drug Metabolism and Safety Toxicity Testing Services that deliver human translatable insights from lead candidates in a few weeks and at lower cost than animal studies. By accessing the Company’s expertise and advanced in vitro liver-on-chip models, these Services enable researchers to step beyond standard in-house laboratory workflows for better informed pre-clinical decisions.

Fast-track your route to successful NASH therapeutic development with CN Bio's 3D NASH model.

Fast track precise spatial multiplexing

Ultravap™ Levante Nitrogen Blow-Down Sample Concentrator

96-Channel Positive Displacement Sample Transfer

We offer extensive Toxicity & Safety Evaluation Services to identify potential risks in drug candidates early. Our comprehensive capabilities cover General, Local, Developmental, and Organ-Specific Toxicity (including liver, cardio, and neuro) across numerous animal species, administered via various routes, to characterize drug safety.

Creative Biolabs delivers expert Genetic Engineering Model Development. Their core expertise lies in utilizing CRISPR/Cas9 and TALEN to create precise Knockout, Knockin, Knockdown, and Humanized mouse models, providing powerful, custom tools for advanced disease research and therapeutic testing.

We specialize in Humanized Mouse Models, overcoming species limits for in vivo human-specific disease studies. We construct diverse systems, including Immune Checkpoint knock-in and PBL/SRC SCID mice, by engrafting functional human cells to power crucial research in oncology, infectious diseases, and immunity.

The NucleoCounter® SP-100™ sperm cell counter offers unique ease of use and effective determination of total sperm concentration and viability in semen samples from ejaculates or extended doses. The NucleoCounter® SP-100™ is very simple to operate and the measurements can be performed by operators with only limited training in laboratory work.

Manufactured under strict Good Manufacturing Practice guidelines, these proteins are designed for use in preclinical, clinical, and therapeutic applications where quality and regulatory compliance are paramount.

Monoclonal and polyclonal antibodies with validated performance for the precise detection of disease biomarkers in a wide range of clinical and research immunoassays.

Recombinant proteins specifically relevant as E3 ligases or target proteins for Proteolysis Targeting Chimeras (PROTACs), enabling the development of this novel targeted protein degradation technology.

The CD34 humanized NSG-FLT3-IL15 (F15) mouse is the most comprehensive immune cell mouse model from the Jackson Laboratory to date.

GenScript’s Enceed™ T cell Activation Reagent is a biocompatible, non-toxic solution designed for the in vitro activation and expansion of human T cells from PBMCs or enriched T cell populations. Utilizing nanosized particles coated with anti-CD3 and anti-CD28 antibodies, it ensures high-fold expansion with a stable memory phenotype, maintaining high cell viability for enhanced downstream applications.

Accelerate precision oncology with Crown Bioscience’s high-quality human biospecimens—comprehensive, clinically annotated samples including tumor tissue, plasma, and PBMCs, optimized for multi-omics research and biomarker discovery.

High fidelity, flexible subcellular proteomics for rapid and quantitative spatial phenotyping

Accelerate Drug Discovery with Crown Bioscience's Comprehensive DMPK / ADME Services

Cell Line-Derived Xenograft Models, Established multiple in vivo assay systems to evaluate novel anticancer compounds, with each assay specifically designed to understand a drug's mechanism of action, or an individual agent property.