Drug discovery > Lead Discovery Products & Reviews

Used in a wide range of validated methods

Peptide maps generated by RP-HPLC provide valuable information about protein structure, stability, and purity. To be effective, the RP-HPLC column must be able to resolve a high percentage of the peptides in the sample. The more peptides, the better the information. Discovery BIO Wide Pore C18 gives unsurpassed RP-HPLC resolution of peptide maps from enzymatic digests. The improvements in silica and bonded-phase chemistry we h…

Easily separate N-1 failure sequences from target oligo with > 90% purities

SecurityGuard offers a convenient and economical way to extend HPLC column lifetimes. Did you know a common cause of high backpressure, split peaks, broad peaks, baseline noise, baseline drift and loss of resolution is contaminants? The fact is all mobile phases contain some chemical contaminants or microparticulates, from the sample, solvent, or wear on the polymeric seals of the pump or injector. These contaminants can…

Accessories and Consumables for FTIR and Dispersive IR instruments to fit virtually any manufacturer's instrument. But before you choose just any accessory check out the MIRacle and GladiATR. Not only the highest throughput single bounce diamond ATRs, but with robust Hastelloy top plates make for maximum durability and acid resistance. With an optional digital 'true force' gauge. These are truly remarkable accessories. Wi…

Cisbio offers a line of three ready-to-use assays for measuring cAMP using HTRF® technology. Each kit is optimized for detecting a specific range of cAMP concentrations to allow fine tuning of assay sensitivity. These kits enable high quality, cell-based assay screening in 96-, 384- or 1536-well formats.

LabSolutions is Shimadzu´s software series for chromatography (GC, GCMS, LC, LCMS). The unified graphical interface makes it easy to work with Shimadzu chromatography products. The GCsolution and GCMSsolution is the perfect partner for the Shimadzu GC and GCMS product range. The GCsolution controls the GC-2010 and GC-2014 (from Ver. 2.3) as well as the previous models GC-14 and GC-17. The GCMSsolution Ver. 2 controls the GCMS-…

The IRAffinity-1S FTIR spectrophotometer has been designed with teaching and general research laboratories in mind. Despite its compact design, it offers full functionality for all FTIR techniques, including transmission, diffuse reflection, and attenuated total reflection (ATR). The full-sized sample compartment accommodates a wide variety of accessories to meet a diverse range of application requirements. Features include…

Shimadzu introduces a new generation of FTIR instruments in the infrared product line with the IRPrestige-21. This new instrument is a conception for high sensitivity as well as for broad applications in the research and development area. The IRPrestige-21 is an outstanding addition to the already existing FTIR product line, which is suitable for general laboratory applications.

PCR Arrays are the most reliable tools for analyzing the expression of a focused panel of genes. Each 96-well or 384-well plate includes SYBR Green-optimized primer assays for a thoroughly researched panel of relevant, pathway- or disease-focused genes. PCR Arrays can also be customized to contain a panel of genes tailored to your specific research interests. Our high-quality primer design and master mix formulation enable the…

Rezex™ columns achieve separations based on multiple modes of interaction including ion-exchange, ion-exclusion, size exclusion, reversed phase, and partition. From drug formulation analysis to quality control testing of finished food products, to bioethanol fermentation monitoring Rezex columns consistently provide accurate and reproducible results.Choose Rezex for excellent resolution and reproducibility of sugars, starches…

Thermo Scientific ABgene 1.2ml Storage Plates are manufactured and in a class 100,000 clean room environment to ensure that each plate is contamination free. Plates are made using virgin medical grade polypropylene and have highly polished surfaces making them low binding and chemically resistant. Rigid side walls and industry standard footprint make plates suitable for automation and robotic handling, as well as for low throu…

Acrodisc PSF syringe filters are available in many membrane types, sizes, and packaging configurations to fit all applications. These are the only syringe filters to receive Caliper Life Sciences Automation Certified guarantee, providing: Smooth operation and worry-free performance in automated applications with smooth filter-to-filter release, consistent turret advancement, exceptional housing strength, and strict outside f…

Full-, semi- or non-skirted 96-well PCR plates with different profiles. Ultra-rigid plates for robotic applications.

The Parker domnick hunter H-Range hydrogen generator with highly sophisticated software control and alarm capabilities presents the GC user with the opportunity to reap all the benefits offered by hydrogen, at an affordable price without the need to worry about safety and environmental factors associated with cylinder-based supplies. H-MD generators are available in three models to deliver varying flow rates of ultra high puri…

Imagine preparing assay plates for siRNA screening, compound screening with biochemical and cell-based assays, PCR reactions and more all on a single liquid handling platform, with no tips and no cross-contamination. Labcyte has developed new acoustic droplet ejection (ADE) parameters that deliver built-in intelligence to enable users to transfer many different fluid types from a single instrument. All Echo systems come pre-ca…

The LCQ Fleet delivers rich information for routine analysis of complex samples with high-throughput and provides excellent full-scan sensitivity, ruggedness and reliability. From the inventors of benchtop LC/MS ion trap technology, this reliable and easy to use ion trap mass spectrometer offers exceptional analytical value while providing confident sample analysis. The new cost effective LCQ Fleet delivers rich information f…

A novel thermoreversible gel mountant for extended immobilization and imaging.

Available retention mechanisms include reversed phase, ion exchange, normal phase and mixed mode

R&D Proteome Profiler Antibody Arrays R&D Proteome Profiler Arrays allow for the measurement of multiple proteins in a single sample. These arrays require no specialized equipment, and eliminate the need for multiple immunoprecipitation/Western blot experiments. R&D Array kits contain buffers, detection antibodies, and membranes spotted in duplicate with capture antibodies carefully selected for their specificity. R&D Arrays…

The Q-Tof micro™ is a high resolution oa-TOF mass spectrometer that provides automated exact mass measurements in an easy-to-use benchtop instrument. It also features a quadrupole mass filter and collision cell for MS/MS analyses, making for a powerful combination that delivers simple exact mass measurement of fragment ions to yield increased confidence in structural elucidation and databank search results. The high-quality da…

The Breeze™ 2 HPLC System delivers technology and performance in an affordable, compact, and user-friendly system platform. Complete with software, pump, detector and injector, the system comes pre-configured for different levels of HPLC operational needs. From teaching purposes to daily analytical work, the Breeze 2 HPLC System integrates simplicity, sensitivity, accuracy, and reliability. It is ideal for any organization see…

The latest development in high shear lab mixing – the new Silverson L5 Series – is ideal for all laboratory work, research and development, QA analysis and small scale production in all industries. The L5 Series Laboratory Mixer is suitable for the widest range of applications – mixing, emulsifying, homogenising, disintegrating and dissolving – with an efficiency and flexibility unmatched by other machines. With a capacity…

The large capacity SC154 Hot Block will digest up to 54, 50mL samples simultaneously in just a 15 X 21.5" footprint. Constructed of Graphite and Kydex® the corrosion-resistant SC154 was designed for environmental and other acid digestions prior to metals determinations. The SC154 uses a maximum of 1065 watts of power and will maintain sample uniformity to ±1.5°C. Heat is provided by a low-wattage heating mat that provides extr…

R&D GM-CSF -Recombinant Mouse Protein GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. Specifications and Use for R&D GM-CSF Source of R&D GM-CSF • A DNA…