Drug Discovery & Development Products & Reviews

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Through extensive research, experimentation, and clinical trials, experts in the field of drug discovery and development identify promising biopharmaceutical or pharmaceutical drug candidates, optimize their efficacy and safety profiles, and navigate regulatory processes for eventual market approval. From innovative therapies to groundbreaking treatments, this dynamic scientific field plays a pivotal role in revolutionizing medicine and saving lives.

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synthWAVE microwave synthesis system

Milestone

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

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flexiWAVE Microwave Synthesis System

Milestone

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

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Lynx Certified Disposable Tips

Dynamic Devices

Lynx Certified Disposable Tips are manufactured in GMP clean-room conditions, with gamma irradiation and in-line visual QA inspection, ensuring sterility and reliability. Packaged in ANSI-standard tip boxes, they integrate seamlessly across Lynx decks—making tip handling safe, flexible, and maintenance-free.

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Metabolite Identification (Met ID) for Peptides

ChemPartner

Our Metabolite Identification service for peptides utilizes HRMS to characterize peptide metabolism (e.g., hydrolysis, oxidation, glucuronidation). The assay identifies and semi-quantifies metabolites in plasma/tissues, enabling ADME profiling (clearance, bioavailability), toxicity screening (reactive metabolites) and peptide optimization (PK/PD enhancement). Integrated with preclinical data, it supports metabolically stable p…

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Comprehensive In Vitro Proarrhythmia Assay (CiPA) for Proarrhythmic Risk Assessment

ChemPartner

Our Comprehensive In Vitro Proarrhythmia Assay (CiPA) service assesses proarrhythmic potential of compounds beyond hERG inhibition, integrating effects on multiple cardiac ion channels and human iPSC-derived cardiomyocytes via patch clamp and multi-well MEA platforms. Aligned with FDA's CiPA initiative and ICH E14/S7B guidelines, it predicts QT prolongation and TdP risks for enhanced specificity in early drug safety evaluation…

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In vitro ADME Protein Binding Platform

ChemPartner

Our Protein Binding Platform assesses drug-protein interactions using equilibrium dialysis and ultracentrifugation methods to determine unbound fractions and distribution in biological samples including plasma, blood, tissues, and cells. This essential ADME service evaluates reversible drug transfer between compartments, providing insights into pharmacokinetics, bioavailability, and potential interactions.

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hERG Safety Screening for Cardiac Toxicity

ChemPartner

Our hERG Safety Screening service employs the Synchropatch-384 automated patch clamp system to assess compound effects on the hERG potassium channel. This high-throughput assay detects inhibitors that may prolong QT intervals and cause arrhythmias, aiding early drug safety evaluation. With precise data under physiological conditions, it supports regulatory compliance to advance safer therapeutics. 

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