Drug Discovery & Development Products & Reviews

Our Metabolite Identification service for Antibody-Drug Conjugates (ADCs) applies immuno-capture and HRMS to detect payload-containing catabolites, linker cleavages, and biotransformations in biological samples. This targeted assay quantifies free payloads, metabolites, and intact conjugates, assessing stability and off-target risks. Essential for ADC development, it informs payload design and pharmacokinetics, ensuring compli…

Our Cassette and Discrete PK Study service evaluates pharmacokinetic profiles of small molecules in key preclinical species: rat, mouse, dog, and monkey. It uses cassette dosing for high-throughput screening of multiple compounds simultaneously and discrete dosing for precise individual assessments for ADME parameters. This aids in early drug optimization, predicting human PK, and ensuring regulatory compliance for safer candi…

The ecTOF is the world’s first GC-HRMS with simultaneous acquisition of EI (Electron Ionization) and CI (Chemical Ionization) information in a single injection. While using EI as the gold-standard GC/MS ionization, the ecTOF in parallel operates a novel CI source. This way it simultaneously provides perfectly aligned accurate mass structural and molecular ion information within a single GC run.

The timsMetabo™ is uniquely designed to deliver unprecedented sensitivity, separation power and annotation confidence for small molecules. Bruker’s technology and workflow innovations combine depth and selectivity for the ultimate in profiling and targeted applications.

Accelerating radiopharmaceutical development in oncology

A compact benchtop design that incorporates 2 or 10 individually powered, high-output stirring stations which can prepare samples for content uniformity testing up to 90% faster than conventional methods.​

Rainbow is an in-situ, fiber optic probe-based, concentration monitor that measures concentration and changes in concentration in real-time without the need for sampling.

Sirius T3 measures pKa, log P, and the solubility of ionizable drugs and small molecules using sub-milligram quantities of samples.

Pion’s PAMPA high-throughput permeability assay uses a range of membranes to mimic physiologic conditions. It allows you to evaluate the passive permeability of API’s as well as the absorption potential of simple or complex formulations using robust models and protocols in a 96-well format.

The SCISSOR is an in-vitro subcutaneous injection site simulator that provides biopharma scientists insights into the behavior of their sub-Q drug candidates.

From small-scale R&D to large-scale manufacturing, Pion homogenizers deliver exceptional fluid processing for particle size reduction (micronization,) cell disruption, and the creation of stable micro- and nanoemulsions and dispersions. Built for scalability, we make the transition from lab to commercial production seamless. Trusted by pharmaceutical, biotech, cannabis, chemical, and food and beverage manufacturers worldwide.

Achieve ultra-high RNA yields with MEGAscript™ kits—ideal for in vitro or in vivo translation studies needing unlabeled or low specific activity RNA.

Discover a world of possibilities with Invitrogen Vivofectamine Delivery Solutions. Rationally designed for in vivo delivery of nucleic acid vaccines and therapeutics, Vivofectamine products and services offer you a distinct edge in basic research and therapeutic development with LNP technology.

Simplify synthesis and scale-up of potent mRNA with third-generation CleanCap®—proven technology for enhanced in vivo translatability.

Hypoxia Workstation

Compact Hypoxia Workstation

Larger-format Hypoxia Workstation

Anaerobic & Microaerophilic Workstation

Anaerobic Workstation

Assay (GC): ≥ 99.0%

Biotage® VacMaster™ Sample Processing Manifolds allow samples to be processed simultaneously under vacuum. Easy-to-use vacuum controls provide excellent sample flow control, leading to reproducible, reliable extraction conditions.

Lyse or homogenize the toughest samples in seconds. Biotage® Lysera is an advanced, easy-to-use bead mill homogenizer designed for rapid, efficient grinding, lysing, and homogenizing of diverse biological samples. With a compact front-loading design, 99 programmable settings, temperature monitoring, and a wide range of accessories, it delivers reproducible results for any sample type without downtime between runs.

Biotage® Extrahera™ Peptide automates sample workup with precision and ease. Designed for synthetic labs, it enables automated solid phase extraction (SPE) and catch-and-release purification of up to 96 samples simultaneously. Positive pressure processing and complementary consumables ensure consistent, high-purity peptide samples free of catalysts and excess reagents.