Drug discovery > Basic Research Products & Reviews

2 ml, 2x real-time PCR mix, contains dNTPs, Sso7d fusion polymerase, MgCl2, EvaGreen dye, stabilizers, for 200 x 20 µl reactions

Measures Color the Way You See ColorTo maintain maximum measurement stability, LabScan XE automatically checks and adjusts to an internal reference standard. To accurately measure optically brightened materials, ultraviolet calibration and control of the illumination source is available.Use LabScan XE to measure samples in virtually any form including solids, powders and liquids. The system can be used in sample port-up, port-…

The Crystal Screen and Crystal Screen 2 reagent kits are designed to provide a highly effective and rapid screening method for the crystallization of macromolecules. The screens are simple and practical for finding initial crystallization conditions. The initial crystallization conditions for more than 1,000 proteins, peptides, oligonucleotides, and small molecules have been determined using Crystal Screen.A highly effective…

Originally published in 1991 by Jancarik & Kim from conditions found to be successful in the crystallization of biological macromolecules. This classic standard sparse matrix screen lets you: Determine initial crystallization conditions. Establish the solubility of a macromolecule in a varying range of pH and precipitants. and with the enhanced buffer selection enables screening of greater crystallization space.Structure Scre…

PEG/Ion, developed by Hampton Research, is a crystallization screen designed to evaluate monodisperse, high purity Polyethylene glycol 3,350 and 48 unique salts representing a very complete range of anions and cations frequently used in the crystallization of biological macromolecules. The primary screening variables are PEG, ion type, ionic strength, and pH. More than 60% of the published crystallizations utilized PEG as a p…

SaltRx was developed by Hampton Research as a primary and secondary, salt and pH based crystallization screen for biological macromolecules. Salt is the only primary crystallization reagent (precipitant) utilized. Based on a design of 96 conditions, the screen evaluates a broad portfolio of crystallization salts of varying concentration and pH.SaltRx can be used as a primary crystallization screen when salt, ionic strength an…

Index is designed as a 96 reagent crystallization screen that combines the strategies of the grid, sparse matrix, and incomplete factorial screening with traditional, contemporary, and new crystallization reagent systems into a highly effective and efficient format. Index, as the name implies, efficiently samples a series of specially formulated reagent zones to identify which reagent class or classes and pH are effective in…

Thermo Scientific™ SPECTRONIC 200 is the new standard for rugged, simple-to-use visible spectrophotometers for teaching and routine applications. The new SPECTRONIC 200 spectrophotometer couples the simplicity and reliability of the SPECTRONIC 20 and GENESYS 20 instruments with 21st century technology and a bold new design that promises years of trouble-free performance.The system is a rugged, simple-to-use spectrophotometer…

The SQ Detector 2 is compatible with the broadest range of chromatography platforms and ionization sources, the SQ Detector 2 is the ultimate single quadrupole mass detector for chromatography.IntelliStart™ guarantees maximum system performance and usability for reproducible results. A wide mass range enables uncompromised analysis of both low and high molecular weight species while versatile chromatographic options ensure com…

Increase productivity by enabling to grow more cells faster and easier. 3- or 5-layer formats provide 525 cm2 and 875 cm2 cell growth surface area, respectively.Even distribution of media across all layers for homogeneous cell growthAbility to mix cells and reagents in the Falcon Multi-Flask saves time and reduces risk of contaminationFlexible design allows to pour or aspirate/recover cells using a pipetConsistent surface trea…

nanoLiter Cool Wave Dispenser - Major sensitivity and repoducibility increases for ESI & MALDI Nanoliter dispensing devices can be used to place media on the MALDI plates for MALDI/TOF instruments, but the most exciting ability of this device is to collimate droplets directly into the ion source like electrospray (ESI), the unique concept being that nearly 100% of the droplets go directly into the source versus <1% from ESI,…

100 reactions, 10 ml, contains100 reactions, 10 ml, contains RNA stabilizers

GC capabilities for today's advanced MS technologies

Individual reagents from the Grid Screen Ammonium Sulfate and Grid Screen Salt HT screens. Grid Screen Ammonium Sulfate Individual Reagents Features: 185 ml volume Sterile filtered Applications: Individual Grid Screen Ammonium Sulfate and Grid Screen Salt HT screen reagents for screening, optimization and production

These Zensor screen printed electrodes (SPEs) feature a carbon working electrode (central circle), carbon auxiliary (outer annular crescent) and Ag/AgCl pellet reference electrode. They can be used as low cost disposable electrodes in aqueous solutions of moderate pH. Disposable SPEs can be used as an alternative to expensive glassy carbon or platinum electrodes for teaching experiments, or routinine analyses, where a clean r…

Raman imaging has never been so fast! Incorporating unique and powerful functions in a reliable, high performance system, ideally suited to the research and analytical lab, the XploRA PLUS is our best multi-sample, multi-user Raman microscope ever.It is fully confocal, not compromising image quality, spatial or depth resolution. The SWIFT Fast Raman images are the fastest fully confocal Raman images available, typically 10x f…

The PacBio RS II is a Single Molecule, Real-Time (SMRT®) DNA Sequencing System that provides the highest consensus accuracy and longest read lengths of any available sequencing technology. SMRT Sequencing is ideal for de novo assembly, characterization of genetic variation, methylation analysis, microbiology studies, and more.The instrument features high performance optics, automated liquid handling, and an environmental cont…

Dominating the high-throughput sequencing data analysis challenge We have overcome the challenge to analyze high-throughput sequencing data faster than it is produced by implementing a SIMD-accelerated assembly algorithm in our next generation sequencing solution, CLC Genomics Workbench – a cross-platform desktop application with a graphical user-interface. CLC Genomics Workbench, for analyzing and visualizing next generation…

Streamline your PCR workflows by consolidating protocols and reaction conditions, increase pass rates, amplify difficult templates without bias, and increase sensitivity – all with a single enzyme. The second-generation KAPA2G Robust DNA Polymerase was evolved to solve - achieve consistent amplification across a broad range of amplicon types (both GC and AT-rich). The versatility and robustness of the polymerase allows for con…

Diagenode’s ultimate solution for long fragment library preparation between 2kb and 75kb– the Megaruptor® fragmentation system. A number of applications for massively parallel sequencing, also known as Next-Generation Sequencing, require libraries of long DNA segments, but few methods have been available for reliably generating fragments greater than 2 kb. The Megaruptor, which has been used by several sequencing centers w…

Combining superior analytical performance with class leading reliability, the 20-22 ensures that all your scientific needs are met. Backed by over 20 years of development with a no compromise approach to its engineering integrity, Sercon provides the ultimate isotope ratio mass spectrometer. This technology is available in both continuous flow 20-22 and dual inlet GEO 20-22 forms to be interfaced with our range of automated p…

Fast ID is a single, easy-to-use DNA extraction kit suitable for a variety of sample types. Fast ID provides high yields of exceptionally pure DNA from a wide variety of sample types including seeds, fruits, vegetables, plants, microbes and clinical specimens. Fast ID contains powerful denaturants and DNA-selective reagents that are specifically designed to prevent DNA degradation and to remove contaminants that might inhibit…

The Qube is Sophion's next generation high-throughput system for ion channel screening, intended for use in laboratories with a need for thousands of data points per day. The Qube finally bridges the gap between high-throughput and high quality in ion channel assays.The Qube can be used for primary and secondary screening of any ion channel of interest. Sophion's vast experience with planar patch clamp from the QPatch products…

The Invitrogen™ Attune™ NxT flow cytometer can be designed to accommodate the most common fluorophores and fluorescent proteins used in flow cytometry to match the panels you are currently running. Multiple fluorescent proteins can be detected with an optional 561 nm laser. Whether you configure your system now or upgrade later, the Attune NxT flow cytometer can grow with you and your research needs. The Attune NxT flow cyt…

Cellometer Auto 2000 Cell Viability Counter for Primary Cells. The Auto 2000 utilizes bright field imaging and dual-fluorescence imaging to quickly and accurately identify and count individual cells. Cell count, concentration, diameter, and % viability are automatically calculated and reported.The Cellometer Auto 2000 is specifically optimized for analysis of primary cells from peripheral blood, cord blood, bone marrow, and o…