Drug discovery > Basic Research Products & Reviews

The Vesicle Prep Pro is a stand-alone workstation for the automated preparation of solvent-free giant unilamellar vesicles (GUVs). The GUVs are formed by means of electro-swelling, ranging from 1 - 30 µm in diameter.

Remove the guesswork. SONICC ® finds protein crystals that other technologies cannot. The ultimate imaging technology in visualizing protein crystals, Second Order Nonlinear Imaging of Chiral Crystals (SONICC) definitively finds crystals buried in precipitate or submicron crystals naked to the eye. 

Crystal Clear Imaging. Unparalleled Speed. ROCK IMAGER ® - Crystallization Imagers are a series of automated imaging systems designed for protein crystallization screening. Capture superior quality images of your protein drops while learning critical information about your crystals. ROCK IMAGERs are available with various plate capacities and imaging features, so there is a model to fit every lab's budget and workflow.

KBiosystems DT-24 and DT-108 Thermal Cycling PCR systems are an alternative way of carrying out medium and high throughput PCR protocols on DNA replication and incubation to micro well format plates. Conventionally peltier heat transfer units have been used to carry out these operations, these however can prove costly to increase productivity throughput and do not optimise the yield potential of carrying out such thermal op…

The CosMx Spatial Molecular Imager is an FFPE-compatible, single-cell imaging solution that enables researchers to investigate intact tissues through the power of spatial multiomics.

Eppendorf Mastercycler is the economical option when, after having optimized your PCR using Mastercycler gradient, you wish to carry out an experiment with the usual Mastercycler quality, but without blocking your optimization cycler.The entire Eppendorf Mastercycler family boasts the personal card system. Chip-based memory cards enable not only simple and reliable transfer of your individual protocols between different Master…

Eppendorf® twin.tec PCR plates give you the advantages that come from combining two materials: the wells are manufactured from virgin polypropylene, the most successful material used for PCR tubes; polycarbonate, an especially rigid material, forms the plate deck and the skirt. This one-piece design is achieved by an innovative injection moulding process, twin-shot technology. Polycarbonate enhances the mechanical stability an…

The Biochrom 30+ Amino Acid Analyzer is trusted by hospitals, reference labs, pharmaceutical and industrial labs worldwide. It accurately detects and quantifies amino acids and their derivatives in complex samples. Applications include: detection and monitoring of in-born errors of metabolism, PKU testing, clinical analysis, proteomics, drug synthesis, infusion fluids, and quality control. The system is based on cation exc…

The Finnigan TSQ Quantum Series of mass spectrometers are the most advanced and powerful triple quadrupole mass spectrometers available. The Quantum Series mass spectrometers feature the patented HyperQuad™ mass analyzer technology, a rugged orthogonal source, and a completely redesigned analyzer geometry for maximum sensitivity, precision, and reliability. The Quantum Series triple quads are the only commercial triple quads a…

This advanced, high performance ion trap - Fourier Transform mass spectrometer is the right tool for your toughtest analytical challenges in metabolic studies, proteome analysis, pharmaceutical discovery, and all other applications. Product detail: The Finnigan LTQ FT™ combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power…

Small-Scale Automation with Large-Scale Results   Access™ laboratory workstations multiply the benefits of the Echo® liquid handler by improving overall assay throughput and reproducibility. With the ability to integrate a variety of devices and the modularity to scale when needed, each workstation offers the flexibility required by frequently-changing assay requirements.  All Access workstations are optimized at install and i…

Recombinant protein A covalently bound to magnetic beads. These beads provide users a rapid, reproducible and efficient reagent for collecting immunocomplexes for chromatin immunoprecipitations (ChIP) assays. Compared with conventional protein A agarose beads, protein A magnetic beads significantly reduce the handling time and mechanical stress on target immunocomplexes.

This kit provides the reagents required for the detection of citrulline-containing proteins by Western blot analysis with the anti-Citrulline antibody. Detection is a two-step process in which citrulline-containing proteins immobilized on nitrocellulose or PVDF are formaldehyde-cross linked to the membrane to improve protein retention, followed by modification of citrulline residues with 2,3-butanedione monoxime and antipyrine…

The ChIPAb+ EZH2, clone AC22 antibody/primer set includes the EZH2, clone AC22 antibody, a negative control antibody (purified mouse IgG), and qPCR primers which amplify a 135 bp region within the promoter of the human MYT-1 gene. The EZH2, clone AC22 antibody and negative control antibodies are supplied in a scalable "per ChIP" reaction size and can be used to functionally validate the precipitation of EZH2-associated chromat…

Protein G covalently coupled by cyanogen bromide to highly cross-linked 4% agarose beads. Stable in all aqueous buffers used in Protein G chromatography.

Beta-Galactosidase Tissue Stain Base Solution. It is one of the components required to visualize the expression of the LacZ reporter gene in fixed tissue.

The UPSTATE colorimetric STAR (Signal Transduction Assay Reaction) ELISA kit is a solid phase sandwich enzyme linked immunosorbent assay that provides a fast, sensitive method to detect specific levels of signaling targets in whole cell extracts. The AKT1 plate is coated with a specific mouse monoclonal anti-AKT1 capture antibody on the microwells of the 96-well clear plate. Many of the reagents are supplied in ready-to use fo…

The MILLIPLEX® MAP Rat Thyroid Hormone TSH Panel - Single Plex is used for the simultaneous quantification of the following Rat analytes: TSH

The MILLIPLEX® MAP Rat Stress Hormone Panel is used for the simultaneous quantification of the following Rat analytes: ACTH, Corticosterone, Melatonin

The SENTERRA II defines a new level of spectroscopic performance and user friendliness in the class of compact Raman microscopes. SENTERRA II is designed to deliver excellent sensitivity combined with high spectral and imaging performance. Therefore the SENTERRA II is a powerful platform for advanced research applications. Due to its high degree of automation, compact size and efficient workflow the SENTERRA II is likewise an…

The compact, benchtop ViBE BioAnalyzer is the ideal research tool for assay development or small to medium size studies which require highly-sensitive detection and quantitation of proteins in complex biological mixtures with real-time results. The small foot-print BioAnalyzer can be easily scaled-up to a ViBE Workstation for higher throughput and walk-away operation. The ViBE BioAnalyzer   •  Ideal for research applications a…

The Applied Biosystems 7500 Fast Real-Time PCR System offers maximum performance in the minimum time. Fully optimized for Fast cycling, the 7500 Fast delivers high-quality results in as little as 30 minutes. Specially designed Fast block ensures thermal uniformity at top speeds Faster ramp rates enable rapid results without compromising extension times or assay quality Fast optical plates ensure excellent precision in 10-30 uL…

The Mai Tai Series Advantage • Highest peak power for deepest penetration and strongest multiphoton fluorescence signal• Shortest pulses for lowest photodamage and photobleaching• Widest dispersion compensation range delivers shortest pulses to the sample (DeepSee)• Wide tuning range for efficient excitation of all commonly used fluorophores• Outstanding pointing stability eliminates the need to realign experimental step-up• F…

The Yanus IV Digital Scan Head is designed for fast scanning of a focused laser beam in the sample plane of a microscope. Typical applications are FRAP or photoactivation. The Yanus IV is used as: • An accessory for the iMIC Digital Microscope and mounts on to the Polytrope Imaging-Mode Switch  • A stand alone component to be integrated into an optical setup like multi-photon microscopy, optical tweezer, STED, etc. As an iMIC…

Multi-label imaging without cross-talk As biological imaging becomes more about studying complex systems rather than single events, Nuance multispectral imaging systems let you quantitate multiple molecular markers even when they are co-localized in a single tissue section, producing clear and accurate images of each individual label on a multi-label tissue section. TRIO is the newest addition to CRi’s award-winning Nuance mul…