Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Osprey sCMOS

Raptor Photonics

The OSPREY Scientific CMOS camera, model OS4MPc-CL, features a 2kx2k Low noise Scientific CMOS sensor that stands out with its extreme sensitivity, high resolution, high speed and excellent Quantum Efficiency. The camera is peltier cooled, uses a 12 bit A/D converter and offers a standard CameraLink output. The OSPREY camera offers outstanding performance for low light applications, such as high resolution fluorescence imaging…

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Falcon EMCCD

Raptor Photonics

The digital FALCON EMCCD camera, model FA285-CL, combines high sensitivity, speed and high resolution. It uses a peltier cooled Texas Instruments' 1MegaPixel Frame Transfer Impactron device which provides QE up to 65%. It uses a 16 bit A/D converter and offers a standard CameraLink output. The Falcon camera offers outstanding performance for low light applications such as fluorescence imaging, astronomy, electrophoresis, X-ray…

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Kite EMCCD

Raptor Photonics

The digital KITE EMCCD camera, model KI247-CL, combines high sensitivity, speed and high resolution. It uses a peltier cooled Texas Instruments' 640 x 480 Interline Transfer Impactron device which provides QE up to 53%. It uses a 16 bit A/D converter and offers a standard CameraLink output. The KITE camera offers outstanding performance for low light applications such as fluorescence imaging, astronomy, electrophoresis, X-ray…

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Kingfisher CCD

Raptor Photonics

Introducing the Kingfisher CCD, driven by the new Sony ICX674 and ICX694 chips, offering 2.8MP and 6MP resolution. The Kingfisher has 4.54μm x 4.54μm pixels enabling ultra sharp image resolution and QE of up to 77%. The extremely low dark current allows long exposure times, perfect for staring applications. The Kingfiasher camera offers outstanding performance for low light applications such as fluorescence imaging, astronomy,…

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Advanced Infrared 2-colour Microarray Scanner: InnoScan 710IR

Innopsys

Unmatched performance for protein assays.Specifically designed to enhance detection in nitrocellulose protein array applications, the InnoScan 710IR near infrared (NIR) fluorescence scanner from Innopsys has on-board 670 nm and 785 nm excitation lasers to optimize performance by reducing the inherent background from the nitrocellulose. No scanner comes close for optical quality and speed of operation. Full compatibility with t…

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Table Top Laboratory Animal Anesthesia System V1

KF Technology Srl

One dial setting delivers a consistent and safe anesthetic level. Manuals include a "cookbook" protocol which can easily be adapted to your facility's SOP. All waste gases are scavenged for easy evacuation. Breathing circuits allow flat, prone or supine positions with head access. Suitable for mouse, rat, hamster, gerbil, guinea pig, ferret, rabbit, cat, dog or small swine.Positive sealing gasket on induction chambers minimize…

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MED64 (MEA System)

KF Technology Srl

A low-noise multi-electrode array system for in vitro extracellular electrophysiology. The MED64 is a user-friendly multi-electrode array (MEA) system for stimulation and recording of field potentials (extracellular signals) from different areas within a biological sample over hours, days, weeks and even months. Acute or cultured biological preparations are placed or grown directly on a grid of 64 planar microelectrodes, whic…

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Brain Slice Chamber Model BSC

KF Technology Srl

These slice recording chambers are designed to maintain isolated, living tissues in vitro in "interface" mode and allow stable electrophysiological recordings to be made from the preparation. The temperature is controlled by a proportional control heating unit.

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Bioscan BioFLECT™ 400

Bioscan Inc.

The new Bioscan BioFLECT 400 is the first in vivo optical imaging system offering true 360° fluorescence tomography. BioFLECT uses the photon emission data acquired from 360° and a state-of-the-art 3D reconstruction engine to quantitatively reconstruct the 3D spatial distribution of fluorescent probes in live animals. This approach yields superior, consistent resolution, sensitivity and quantitation throughout the subject. The…

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Ultima Multiphoton In Vivo Extended Reach Microscope

Prairie Technologies

The Ultima In Vivo Extended Reach builds upon the In Vivo clearance to provide an even larger area for researchers using larger animals for their imaging models. Mounted on posts that are fixed or movable, the user can choose to move the sample or the microscope itself. Scanheads with the standard imaging galvos and the optional uncaging galvos allow for simultaneous imaging and uncaging using two lasers. Prairie View softwa…

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GoTaq® Probe qPCR Master Mix

Promega Corp.

The GoTaq® Probe qPCR Master Mix is optimized for quantitative PCR assays in the hydrolysis probe detection format.   It is provided as a ready-to-use, stabilized 2X formulation that includes all components for qPCR (except template, primers and probe). This master mix does not contain a reference dye; however, a separate tube of carboxy-X-rhodamine (CXR) reference dye is included with this system, allowing users to add…

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GoTaq® Probe 2-Step RT-qPCR System

Promega Corp.

The GoTaq® Probe 2-Step RT-qPCR System is optimized for quantitative PCR assays in the hydrolysis probe detection format. The system protocol facilitates detection and relative quantification of RNA expression levels via a two-step RT-qPCR method using integrated components: • GoScript™ Reverse Transcription System • GoTaq® Probe qPCR Master Mix The GoScript™ Reverse Transcription System includes an optimized reaction b…

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Perfecta3D Hanging Drop Plates - 384-Well

3D Biomatrix

The patent-pending Perfecta3D® Hanging Drop Plates are 96- and 384-well plates that facilitate the formation, culture, and testing of three-dimensional (3D) spheroids and stem cell aggregates without the aid of coatings or matrices. With only one spheroid forming in each well, 3D spheroids formed in Perfecta3D Hanging Drop Plates are consistent and diameter can be controlled by the number of cells seeded in each well. Media…

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FLS980-sm: Combined Steady State and Phosphorescence Lifetime Fluorimeter

Edinburgh Instruments Ltd.

The FLS980-sm is the world’s most sensitive modular, computer controlled spectrofluorimeter offering combined steady state and phosphorescence capabilities. Combining ultimate sensitivity with high spectral resolution and excellent stray light rejection, the FLS980-sm can measure lifetimes from 1microsecond to 10 seconds. Features Include: Lifetimes from 1 microseconds to 10 seconds. Automated spectral correction PC plug-in ca…

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FLS980-s: Sensitive Spectrofluorimeter - Steady State

Edinburgh Instruments Ltd.

The FLS980-s is the world’s most sensitive modular, computer controlled spectrofluorimeter.Features Include: • Guaranteed S/N ratio of >12000:1 • Count rates of up to 100MHz Resolution from 0.05 – 18nm • Stray Light Suppression of 1 x 105 (1 x 1010 optional) • Automated spectral correction Complete PC control The FLS980-s is a modular, computer controlled L - geometry spectrometer for acquiring steady state luminescence spectr…

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FLS980-m: A Complete Fluorescence, Phosphorescence Laboratory in one Instrument

Edinburgh Instruments Ltd.

The FLS980-m is the world’s most sensitive modular, computer controlled spectrofluorimeter offering phosphorescence capabilities. Combining ultimate sensitivity with high spectral resolution and excellent stray light rejection, the FLS980-m can measure lifetimes from 1 µs to 10 seconds.Features Include: • Count rates of up to 100MHz • Lifetimes from 1µs to 10 seconds • Resolution from 0.06 (with 1800g/mm grating) • Stray Light…

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FLS980-t: High Performance Fluorescence Lifetime Spectrometer

Edinburgh Instruments Ltd.

The FLS980-t is s the world’s most sensitive modular, computer controlled fluorescence lifetime spectrometer. Based on an L - geometry hardware configuration, the FLS980-t utilises the technique of Time Correlated Single Photon Counting (TCSPC) to measure time resolved luminescence spectra and luminescence lifetimes spanning the range from 100picoseconds to 10microseconds, with the accuracy and the resolution that only the tec…

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Snap Seal™ Vials and Snap Top Caps™ for the 96 Well Multi Tier™ Micro Plate System

J.G. Finneran Associates, Inc

Patented sample vials and closures form a sealing system for use with autosamplers and robotic equipment Chemists can secure samples in a snap with a new system for automated high-throughput sampling. J.G. Finneran Associates, a manufacturer and supplier of unique and innovative products for the global chromatography, biotechnology, and environmental research communities, has adapted its Snap Seal Vials and 8mm Precision Fit S…

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CellBase CT - for ex-vivo expansion of autologous cell therapy products

TAP Biosystems

CellBase CT is a new automated system designed for ex-vivo expansion of autologous cell therapy products. Developed with leading cell therapy organisations, CellBase CT scales up existing manual cell culture processes in T-flasks, enabling manufacture of cell therapy products derived from a wide range of cell types, including hES, iPS and adult stem cells. CellBase CT automates:CellBase CT automates the maintenance and expansi…

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ProReveal Test

Synoptics Health

Fluorescence Protein Detection Test ProReveal is a highly sensitive fluorescence-based patented protein detection test for checking the presence of residual protein on surgical instruments after going through a washer disinfector process. This cost-effective test (conforms to BS EN ISO 15883-1) delivers objective, visual and measurable results, removing any doubt as to whether a decontaminated instrument is safe for reuse. Ke…

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MultiPep RSi

Intavis Inc.

The MultiPep RSi is a fully automated high throughput multiple peptide synthesizer based on a pipetting robot. Utilizing exchangeable modules, the MultiPep RSi can be configured to enable the synthesis of small scale peptide libraries, membrane bound peptide arrays (SPOT method), specialty peptides or PNAs, as well as high quality peptides in large scales up to 10 mmol. Due to this flexibility, the instrument can take the pl…

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MultiPep CF

Intavis Inc.

The MultiPep CF is a fully automated peptide synthesizer with a unique column module that allows the synthesis of long and difficult sequences. During the synthesis, reagents are continuously circulated and real time UV monitoring enables the automatic optimization of reaction parameters like deprotection, coupling times, and wash steps. This leads to a greater coupling yield, superior peptides, and also saves time and reduc…

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Liquid Crystal Tuneable Optical Filter

Laser Physics UK Ltd

Meadowlark Optics’ Liquid Crystal Tuneable Optical Filters facilitate spectral analysis of not only a collimated beam, but of an entire object. With no moving parts, a resolution down to 0.001nm and a tuning rate of less than 100ms, these robust filters are calibration free and can replace literally 1000s of filters for applications including fluorescence and absorption microscopy, Raman spectroscopy and solar astronomy. At 38…

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Spatial Light Modulator

Laser Physics UK Ltd

Meadowlark Optics manufactures a range of world leading Spatial Light Modulators (SLMs) providing precision beam control. The 2-dimensional Hex series are designed for adaptive optics applications as real-time programmable phase mask for wave front correction, such as a variable iris with no moving parts. With its high optical power handling characteristics, the Linear SLM can be used to alter the temporal profile of femto sec…

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Photomultiplier

Laser Physics UK Ltd

The Photomultiplier is a turnkey detector with a low noise, high sensitivity system that exceeds the performance of silicon photodiode systems over the wavelength range 185 to 800nm. It has a superior combination of a large, 8mm diameter, aperture and fast response of 10 microseconds. The convenient controller provides 11 gain seconds over an amplification range of 102 to 106 and includes a detector overvoltage protection circ…

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