Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Initiator+ Alstra

Biotage

Microwave irradiation is still the most effective solution for providing a fast, precise and efficient heating method for synthesizing peptides, peptoids, PNA and peptidomimetics with higher purity and yield compared to conventional synthesis methods.

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Biotage Miniprep PhyTip Columns for Plasmid DNA Purification

Biotage

Lysate Direct PhyTip® Column Technology consists of novel purification columns that are composed of a pipet tip containing plasmid DNA binding resin and a thin, inert frit screen at the end of the tip to retain the resin. The unique design of the column allows for DNA binding directly from cell lysates in the presence of precipitates and debris without sample clearing. By eliminating the need for centrifugation or filtration,…

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Biotage® PhyPrep System

Biotage

Biotage® PhyPrep automates the purification of plasmid DNA from cell pellets at the Maxi, Mega and Giga scales. The result is highly pure, endotoxin-free plasmid DNA – the optimal starting point for downstream applications, such as transient transfection. Biotage® PhyPrep comes with everything needed to generate highly pure plasmids, from a simple sample preparation step to a fully automated purification procedure, freeing up…

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Opto™ Assure Aggregation Assay

Bruker Cellular Analysis

As therapeutic molecules become more complex, developing cell lines that make high yield, high-quality product has become more challenging. Opto Assure makes earlier assessment of product quality possible, so you get the best cells and a faster, lower-risk path to volume production – even for complex molecules like bispecifics.

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Beacon® Optofluidic System

Bruker Cellular Analysis

With the Beacon system’s light-speed workflows, you’ll gain insights, iterate and innovate. Replace a roomful of equipment with the Beacon system Work fast with individual cells  Perform assays at any time, as often as you need Track phenotype and genotype of single cells or clones Automate and scale workflows beyond manual, time-intensive analysis Generate great insights through deep profiling of each cell or clone

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Cortisol Saliva ELISA

Tecan

The Tecan Cortisol Saliva ELISA  is an excellent alternative to the current complex and relatively expensive LC-MS/MS method to determine cortisol in saliva as accurately as possible.

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iLite® Functional Bioassays

Svar Life Science AB

The iLite® Functional Bioassay portfolio consists of cell lines provided in an “assay-ready” format for a rapid and convenient workflow. The assay-ready format also reduces assay variability, optimizing its use in screening, characterization, stability, and potency studies. iLite cell lines can be tailored to virtually any biopharmaceutical target.

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iLite® Fc Effector Activity Bioassays

Svar Life Science AB

The iLite® Fc Effector Reporter Gene Bioassays Portfolio offers a variety of reporter gene cell lines and target cells that can be used in MOA-reflective assays to measure the Fc effect of antibodies and other biologics that specifically bind and activate Fc receptors. Using a Luciferase reporter gene system offers a convenient and powerful way of measuring antibodies' in vitro efficacy in triggering ADCC and ADCP.

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Anti-CCP Assay

Svar Life Science AB

In diagnosis of Rheumatoid Arthritis (RA), the measurement of anti-CCP is integral. People who test positive for Anti-CCP, are very likely to develop or have already developed RA, but not all who have RA, necessarily develop anti-CCP. Early detection of RA is crucial for reducing tissue damage.

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CRO Services

Svar Life Science AB

Svar CRO Services provides direct value through an extensive toolbox of in-house products, scientific expertise, and end-to-end customizable solutions – everything to ensure the success of your drug development program.​

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Biomarker Discovery Services

Svar Life Science AB

Expert Biomarker Discovery Services using cutting-edge technologies such as high-quality proteomics with Proximity Extension Assay (PEA) technology from Olink, and ultra-sensitive detection with proven Simoa technology. We offer ideal broad screening-to-targeted biomarker discovery solutions in different therapeutic areas.

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Bioanalytical Services

Svar Life Science AB

A specialized and GxP-certified laboratory for Bioanalytical Service Solutions -with scientific expertise & advanced technologies. We offer assay development, validation, and sample analysis of pharmacokinetics, toxicokinetic, pharmacodynamics, immunogenicity, and biomarker analysis.

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Temperature-Validation System

Eppendorf

The Temperature-Validation System for the entire Mastercycler family enables simple and rapid validation and calibration of the temperature on the universal blocks of the cyclers. The program for automatic measurement and calibration is integrated into the Mastercycler software, thus furnishing the Mastercycler family with an accurate and precise system that meets all documentation and detection requirements in the laboratory.

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CycleManager

Eppendorf

The Eppendorf CycleManager is a Windows based software for programming and controlling one or more Mastercyclers. The thourough databank ensures reliable storage of all GLP relevant experimental data incl. detailed user comments.The main dialogue box is the central user interface. All key functions can be accessed from it. Mastercyclers can be added or removed from the Multi-Cycler-Network. It offers also an overview of all co…

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Cap Strips

Eppendorf

• Strips with 8 microcaps for 0.2 ml wells• Easy and rapid sealing of Eppendorf twin.tec plates and other standard microtiter plates, see also Capping Aid• Easy to remove using extension at the end of the strip• Autoclavable (121°C, 20 min.)• Certified free of human DNA, DNase, RNase and PCR Inhibitor**Certificate, test procedures and detailed information on request.

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PCR Film, adhesive, and PCR Foil, adhesive

Eppendorf

Effective adhesive seal prevents evaporation during reaction and storage Can be removed from plate without leaving any residue Autoclavable (121°C, 20 min.) Certified free of human DNA, DNase, RNase and PCR Inhibitor*1 PCR Film, adhesive Sample can be visually monitored through the transparent film PCR Foil, adhesive Easy to pierce Pipette tip does not become tacky (ideal for automated systems) *1 Certifi…

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