Drug discovery > Target Discovery Products & Reviews
Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
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Duolink In Situ Red Starter Kit Mouse/Rabbit
MerckApplication Duolink® proximity ligation assay(PLA®) allows for endogenous detection of protein interactions, post translational modifications, and protein expression levels at the single molecule level in fixed cells and tissue samples. Follow the Duolink® In Situ Fluorescence Protocol to use this product. A set of short instructionsis also available. Visit our Duolink® PLA Resource Center for information on how to ru…
Amnis® Imaging Flow Cytometers
MerckCombining microscopy and flow cytometry, Amnis imaging flow cytometry systems provide bright-field, dark-field (SSC), and several fluorescent images of each cell in flow, at high speed. Paired with IDEAS® software for quantitative image analysis and population statistics, the technology gives you the ability to address complex biology that traditional flow cytometers can't resolve. Not only do the instruments reveal spatial lo…
YeastBusterâ„¢ Protein Extraction Reagent
MerckFor fast, reproducible and gentle extraction of active proteins from yeast and plant cells, use YeastBuster™ Protein Extraction Reagent. This reagent avoids the harsh conditions of vigorous mechanical or chemical treatment that often result in degradation of target proteins. Harvest cells and resuspend in YeastBuster™ protein extraction reagent, incubate for 15 minutes and then remove cell debris by centrifugation. Your extra…
BL21(DE3) Competent Cells - Novagen
MerckBL21(DE3) is a chemically competent E. coli  cell suitable for transformation and high level protein expression using a T7 RNA polymerase-IPTG induction system.
Goat Serum, 100 ml
MerckNon-sterile goat serum collected from normal healthy goats. Used for blocking of interfering antibodies.
Cell Proliferation Kit I (MTT)
MerckThe Cell Proliferation Kit I (MTT) is a colorimetric assay for the non-radioactive quantification of cellular proliferation, viability, and cytotoxicity.
2-Mercaptoethanol
MerckFor molecular biology, suitable for electrophoresis, suitable for cell culture, BioReagent, 99% (GC/titration)
Steritestâ„¢ Sterility Media
MerckSterility testing culture media and rinsing fluids are critical components of your Steritest™ solution. They provide the highest level of quality and testing confidence, they have been formulated and tested to meet the requirements of the USP <71>, EU Pharmacopoeia < 2.6.1> and JP Pharmacopoeia <4.06>. Steritest™ sterility culture media and rinsing solutions are manufactured in an ISO 9001, environmentally controlled productio…