Status:
ReviewerMember since: 2021
Organization: Children's Hospital of Philadelphia
Waters' instruments may not be the best, but their services are definitely the best.
Application Area: Infliximab and glutathione analysis
"Waters service is the best among all the other vendors including Aglent, Sciex, Thermo, Shimadzu, and PerkinElmer. Waters' technical support is easier to access and service engineers are usually very helpful. Waters' tripple quads are easy to use and sensitivity is pretty good also. "
Status:
ReviewerMember since: 2020
Organization: NIPER
Great instrument, very robust!
Application Area:Analysis of environmental samples and clinical samples for endocrine disrupting chemicals
"One system. Every analyte. All the time. I really enjoy working on the system. It is one of the best TQD systems. Provides greater sensitivity. The best thing about the system is its ease of use."
Status:
ReviewerMember since: 2020
Organization: Roche
System is robust, easy to handle, low down time and provides reproducible results.
Application Area:Metabolomics
"Robust and high-throughput system for targeted metabolomics. Various options for MRM transitions, multi analyte method with schedule MRM function while providing sufficient data points with fast analysis. Very reproducible results and very low down time, easy to calibrate and clean. Tuning of MS parameters for more than 100 analytes is very fast due to very good automatic tuning function."
Status:
ReviewerMember since: 2020
Organization: Benedictine University
Great instrument, every new MS gets better.
Application Area:Environmental
"High-quality, high-sensitivity, stable platform. Has great software and easy to use."
Status:
ReviewerMember since: 2019
Organization: MTA Agrártudományi Kutatóközpont
Best LC-MS/MS systems I have ever used & UNISPRAY! (used Thermo, Sciex, Agilent, Shimadzu).
Application Area:Plant metabolome analysis, pesticide & mycotoxins, anabolic hormones&endocrine disruptors,
"Very effective especially with the Acquity UHPLC I class system, I also have PDA detector for it. Mass Lynx is great software, nicely enginered and crafted, at first glance there are a lot of windows, but I could get used to it quickly. Optimization can be a bit tricky if you would like to optimize a lot of compounds from a mix, but thats usually an uncommon thing to do. For Pharma its superb. For research its also great, I just liked the Sciex way of optimizing better. Very robust machine, won't punish you for smaller mistakes, and ESI source is good, but you can also do EsCI wth it (kinda like the mix of ESI and APCI) or you can also do UniSpray. What I love is that for most molecules its even unnecesarry to optimize for cone voltage (Sciex call it declustering potential) because it will work at max sensitivity for most molecules around a certain setting, this means less in source fragmentation which is a good thing for most users (for some applications however it's a disadvantage if you want to make in source fragments by increasing the cone voltage - you will have to apply really high levels). Unispray is just great, I had several comparisons for a lot of compound classes UNISPRAY VS ESI and it will increase your sensitivity by a factor of 3-14 and S/N ratio by 3-5 times compared to ESI! It does better in positive mode, but also at least 2.5-3 times enhancements in negative mode also! I've tested this so far only for small molecules, not for proteomics. In the stepwave it's good to use, soft transmission can help you with labile compounds. Instrument uses argon as collision gas, can help with fragmenting stuff thats sometimes not fragmentable with nitrogen, however argon has the disatvantage that it can fairly easily make fragments with low collision energies. In source fragmentation can be limited, also cone gas is great. You can increase it to high levels to protect your instrument and you cannot decrease it below 150 L/H for the protection of your instrument. Source cleaning is fairly fast and easy. I managed to go down to femtogram sometimes even attogram on one column and still detect quantitatively! This can vary from compound to compund. For pesticides its very sensitive, does good for hormones. I have had the instrument for 1 year but I managed to acquire a contract form Waters for a 3 year total warranty and total service and OQ PQ at the end of the 3rd year so thats great. Of course the price was high but no price is high for a very trustworthy LC-MS. Waters has the best customer support at least in Hungary."
Status:
ReviewerMember since: 2019
Organization: Tyson Foods
Required different needle wash solutions to limit carryover.
Application Area:Drug residue
"Required different needle wash solutions to limit carryover. Some needle washes used worked on our Acquity TQD & XEVO TQD, but it didn’t work on TQ-XS."
Status:
ReviewerMember since: 2019
Organization: Mercantil
The best of the best.
Application Area:Pesticides
"We can see the peak on the spectra and the clarity Is amazing I will recommend Xevo TQ-XS"
Demands on analytical laboratories are changing and every laboratory needs to ensure it can keep pace with these changes.
The Xevo™ TQ-XS offers: