Status:
ReviewerMember since: 2011
Organization: Emory University, School of Medicine, Dept of Pulmonary
Great data has come from using this column.
Application Area: Analyze metabolites
"We have tried other HILIC columns and found this to be the best in terms of separation and resolution."
Status:
ReviewerMember since: 2018
Organization: GEPP
Excellent results and technical service at the height of our needs.
Application Area:Laboratory and microbiology
"In my experience as a buyer, according to all the feedback given by the users, it is a very good and optimal product that gives the necessary results."
Status:
ReviewerMember since: 2018
Organization: IRTA
Great results! The most important is the support and the seminars.
Application Area:Analyze marine biotoxins
"High quality and repeatability. We are accredited by ISO 17025. Great results and necessary for our Institute! The most important is the support and the seminars that Waters offers,"
Status:
ReviewerMember since: 2018
Organization: Sintenovo SA de CV
Excellent results.
Application Area:Quality control
"Although it has a high cost, the amount of use is adequate and appropriate."
Status:
ReviewerMember since: 2018
Organization: Result Laboratory
Positive and robust.
Application Area:Clinical diagnostics
"Quality is fine, even with the difficult blood matrix. If a patient has a matrix with very low content of hemoglobin there are sometimes problems. The high number of injections that are possible are a very positive thing."
Status:
ReviewerMember since: 2018
Organization: Univ. Toronto
Excellent HILIC phase for highly charged metabolites but requires some LC experience.
Application Area:Analysis of phosphorylated plant metabolites
"XPBridge amide columns are effective for the separation of highly polar, charged metabolites in HILIC mode. However, extra care must be taken to limit the water content in the mobile phase as swelling may occur, leading to extremely high back pressure or possibly column damage. This column is excellent for the separation of charged metabolites but it cannot run dry or it will be permanently damaged. Not recommended for the LC novice and not as easy to use as a more robust C18 column but very effective for highly polar applications."
Status:
ReviewerMember since: 2018
Organization: University of Helsinki/VERIFIN
Good product!
Application Area:Analysis of CWA's
"Quality columns, robust and long lifetime. Usually works without any problems. All the columns are delivered quickly."
Status:
ReviewerMember since: 2018
Organization: MWSU
Resolution and separation remained constant through the first 500+ injections
Application Area:Developing a method for analysis of steroids in various matrices
"The product was installed and has run perfectly over several hundred injections. I anticipate a useful life that exceeds 1,000 injections."
Status:
ReviewerMember since: 2018
Organization: Innovative Chemical Technologies , Inc.
Reliable results and easy to use
Application Area:Quantify trace levels of substances in finished goods
"We have used this type of column for years and we get great and reliable results each and every time. Installation is quick and easy and the column is very durable. This column is worth the price - we get several years of daily use from it with no issues."
Status:
ReviewerMember since: 2018
Organization: WAVE LIFE
Great results, high pH range stability and temperature endurance.
Application Area:Analyze oligonucleotide
"The results were achieved in expected excellence. We initially compared the XBridge column with a BEH column, they both are excellent, and would be complementary to each other in applications."
Status:
ReviewerMember since: 2018
Organization: Fundación Cidetec
Great results.
Application Area:Analyze peptides
"We used this column in our laboratory to transfer a UPLC method to a new HPLC method. The Technological transfer was very easy and we are very happy with this column."
Status:
ReviewerMember since: 2018
Organization: Roche
Good separationts,
Application Area:Analyze small molecule samples
"Good and solid column, do what they should. Good separation of smal molecules and good resultion of the peaks"
Status:
ReviewerMember since: 2018
Organization: Fa. Hoffmann La Roche
Great column with a lot of robustness and reproducibility.
Application Area:Small molecules, pharma development
"We use these columns in cases of different sensitivity needs. The column has highly reproducible results and is very robust. The sensitivity for our needs is quite good."
Status:
ReviewerMember since: 2018
Organization: Caudalie
Good product.
Application Area:Phytochemistry
"The product was easy too use even if I had a problem with installing the guard column."
Status:
ReviewerMember since: 2018
Organization: Max Planck Inst.Chem.Ecol
Good results, reproducible chromatography. Durability could be better.
Application Area:Analyze polar compounds (sugars and amino acids) in biological samples (insects and plants)
"Good column, chromatography is reproducible and use is relatively easy, being compatible with many of our current mobile phases - although best results were obtained with specific mixtures and different additives than what we commonly use (ammonium formate in pre-mixed solvent mixes instead of aqueous formic acid). Peak shapes OK, a little broad but in line with other polar separation columns we used in the past. Durability could be better, with columns failing/developing high pressures already after a few hundreds of samples."
Status:
ReviewerMember since: 2018
Organization: Miami University
Good column, nice performance.
Application Area:Metabolomics
"The XBridge is at high quality, it provides extremely good reproducibility, which is essential for bioanalytical analysis."
Status:
ReviewerMember since: 2018
Organization: Ghent University
It does what it's supposed to do, great.
Application Area:Beta-alanine, carnosine, anserine, taurine, histidine
"We use this column with HPLC-fluorescence. We obtain reproducible chromatograms with this column. Waters was helpful in providing assistance for optimization and problem solving."
Status:
ReviewerMember since: 2018
Organization: Laboratoire CEISAM
Very satisfactory results for several applications.
Application Area:Kinetics of 5-Fluorouracil
"High performance, meets the requirements for many applications, robust."
Status:
ReviewerMember since: 2018
Organization: F. Hoffmann- la Roche Bldg 97/O02.014.04 Grenzacherstrasse 124 CH-4070 Basel
I recommend the XBridge XP column.
Application Area:Solubility and dissolution of small molecule
"I achieved good reproducibility of the results and ease of use."
Status:
ReviewerMember since: 2018
Organization: Carnegie Pharmaceuticals LLC
Great result
Application Area:Pharmaceuticals Research and Development
"Using Waters products specially HPLC columns is a great experience, I hardly found any pressure issues or any kind of extra-unwanted peaks. It has great resolution. Thank you for providing a great product"
Status:
ReviewerMember since: 2018
Organization: MedPharm
Very useful, would definitely use again.
Application Area:Analyse NCE stability in formulations and solvent systems
"Very robust column, has high efficiency and a long lifetime. Easy to use, in terms of before and after care and is easily fitted into all of our various LC systems."
Status:
ReviewerMember since: 2017
Organization: Takasago Int'l (USA)
Excellent HILIC column
Application Area:Food, flavor, fragrance, consumer products
"BEH Amide excellent HILIC column at various pH's. Great service from Waters."
Status:
ReviewerMember since: 2018
Organization: Insud Pharma
The ratio between endurance and price is the best for any column that I have tested.
Application Area:Analyze an API in a capsule of a dry powder inhalation product
"I am using an C18 100x4.6mm column, with a particle size of 5µm. The column is very useful specially for single-component and fast methods, allowing you to an easy separation with a very short run time. The endurance of the column is beyond remarkable. At average conditions (pressure, column temperature) the column lasts for more than 10.000 injections, sometimes more than 20.000."
Status:
ReviewerMember since: 2018
Organization: DowAgroSciences
A column that each lab must have.
Application Area:Analysis of pesticides
"Robust column, reproducible results, long life time, in summary a column that you have to have in your lab."
Status:
ReviewerMember since: 2018
Organization: QPS, LLC
Wonderful go-to columns
Application Area:Analysis of small molecules in various matrices
"Results were great. Very reproducible and easy to use. I was highly satisfied with my Xbridge BEH C18. This is one of my go-to columns for analysis. The Waters team is there any time I have a question and respond quickly. Very satisfied customer."
Status:
ReviewerMember since: 2018
Organization: IFREMER
to develop for further studies
Application Area:Analyze metabolites from bacterial culture
"Easy to use and good reproductibility of the results even the samples are not always in the same buffer. Good experience."
Status:
ReviewerMember since: 2018
Organization: Zentiva
Try it and you will be satisfied
Application Area:Pharmaceutical industry
"Easy to use, excellent reproducibility, more than 800 injections without bleeding or any changing"
Status:
ReviewerMember since: 2018
Organization: Eurofins BioPharma Product Testing, Columbia
Great results
Application Area:Assay and Impurities analysis of pharmaceutical development product
"It was easy to use and passed all system suitability requirements. We are still currently using the same column for the same method."
Status:
ReviewerMember since: 2018
Organization: University of Warwick, School of Life Sciences
Good mid-priced column worth buying, if it fits your application
Application Area:analysis of polar lipids
"The column works very well for the application in our lab and several different people use it. We use it with eluents acetonitrile and 10 mM ammonium acetate in water at pH 9.2 for HILIC applications. Resolution is good, but we noticed when we try to increase ammonium acetate concentration, although apparently up to 20 mM should be okay, we loose resolution. Over time we found some background signal sticking to the column that is why we bought this new one. We would not use it without a guard, though. Equilibration of the column is straight forward and we got a good resolution and no background with the new column. Thus, really easy to use (well, we already knew the method we wanted to use) - it is all in the manual, although formulations could be written slightly easier, because for some parts we had to discuss whether we did get them right. I do not know what to comment on "after sales care", as I had not been contacted before, but the information before the purchase was good. Regarding the value for money, I understand that UHPLC columns in general are not cheap, so this analytical column is in a mid-price range. I would definitely recommend purchasing the guard with it, although I found it slightly annoying that you could only get it as a pack of three, which made it more expensive."
Status:
ReviewerMember since: 2018
Organization: University of Washington
Good peak shape and reproducibility, great robustness
Application Area:Analysis of metabolites from biological fluids or tissues
"Highly robust and reproducible results from these columns. Not ideal for all classes of metabolites as some peak shapes are very poor quality but the vast majority that we look for good shape and reproducible. We have seen this column successfully handle over 1700 injections"
Status:
ReviewerMember since: 2018
Organization: Productos Maver S. A. de C. V.
Very efficient, highly recommended
Application Area:Analysis of product in process and finished product
"It is easy to use, offers greater efficiency against traditional materials, although the cost is not exactly chear, it is worth the investment."
Status:
ReviewerMember since: 2018
Organization: Chemolee Lab
Might be great with certain conditions.
Application Area:Sunscreen analysis
"After service from Waters is excellent. The column we purchased was very good. However, the resolution between peaks was did not meet our specification. That is why we returned the column."
Status:
ReviewerMember since: 2018
Organization: Austarpharma
Great column for your UPLC applications.
Application Area:Pharmaceutical method development
"The column is robust and easy to use. I purchased a lot of Waters columns for my application. Really good products."
Status:
ReviewerMember since: 2018
Organization: JNJ
reviewed well
Application Area:Pharmaceuticals
"The column performs very well. very good integration..I have not recieved any compliants."
Status:
ReviewerMember since: 2018
Organization: Syneos Health
Versatility, Durability, and Dependability let use XBridge columns with confidence.
Application Area:Analyte/metabolite analysis from human plasma samples
"I've always been a big fan of XBridge columns. Their versatility across wide pH ranges and ruggedness to withstand thousands of injections is ideal for our fast paced CRO environment. High plate counts demonstrate great column efficiency allowing us the versatility to forgo UPLC applications. Column durability and applicability across highly variable analyte chemistries make Xbridge columns very attractive for our workflows."
Status:
ReviewerMember since: 2018
Organization: Gilead Sciences
The column works great
Application Area:Analysis of small molecule pharmaceuticals
"The Waters BEH XBridge XP is robust from column to column and from lot to lot. We are able to get consistent results that do not deviate from the test method parameters and are the expected results from method validation."
Status:
Advanced ReviewerMember since: 2018
Organization: ChemGenes Corporation
Excellent results
Application Area:Oligonucleotide Chemistry
"We have been achieving very high resolution with this column. True and transparent results. One thing about the guard column: it is not lasting long, after a few injections, we have to change the guard column. We had also tried using the column without the guard column and it lasted longer. Hence, guard column needs to be upgraded."
Status:
ReviewerMember since: 2018
Organization: Dominion Diagnostics
Waters Bridge XP columns dependability and consistency have really made a difference.
Application Area:Urine Drug Testing by LC-MS/MS
"We depend on the consistency of these columns for our analysis because of the minimal lot to lot variation. Retention times and column life are always consistent. Any small problem with an LC column has high impact on our lab which processes thousands of samples per day. Technical and customer support are above reproach, which gives us another level of confidence in Waters. The Bridge XP LC columns are first selected for method development by our Research and Development team because of their relatively high recovery, resolution and peak shape for most analytes."
The common base particle for all XBridge BEH HPLC, eXtended Performance (XP) and ACQUITY UPLC Columns provide seamless scalability throughout the available particle sizes (1.7, 2.5, 3.5, 5, and 10 μm). Improve existing HPLC methods 4-fold by selecting a column configuration that provides the correct balance between resolution and sample throughput.
Method Development Flexibility
XBridge BEH XP Columns are designed to eliminate compromise of sorbent selection and deliver the flexibility to work under any mobile phase, temperature and pH conditions. Using a simple method development protocol the most challenging sample mixtures can be efficiently separated. The systematic approach combining mobile phase pH and organic modifier is the fastest path to a modern optimized ultra-high performance (UHPLC) method.
Seamless Scalability
XBridge BEH XP 2.5 µm Columns are high efficiency, low backpressure HPLC columns that can be easily utilized across all HPLC, UHPLC and UPLC Technology platforms. XBridge BEH Columns improve productivity by providing method consistency and flexibility between laboratories - independent of instrument platform.
VanGuard Column Protection
The often complex sample matrices encountered in pharmaceutical, natural product, environmental, and industrial chemical analysis prematurely shorten analytical column lifetime and degrade chromatographic performance. Waters VanGuard Cartridge Columns help improve analytical column performance by removing particulate and chemical contamination that may be present in the mobile-phase stream—without compromising chromatographic performance.