XBridge BEH XP Columns by Waters

"We used this column in our laboratory to transfer a UPLC method to a new HPLC method. The Technological transfer was very easy and we are very happy with this column."

"Good and solid column, do what they should. Good separation of smal molecules and good resultion of the peaks"

"We use these columns in cases of different sensitivity needs. The column has highly reproducible results and is very robust. The sensitivity for our needs is quite good."

"The product was easy too use even if I had a problem with installing the guard column."

"Good column, chromatography is reproducible and use is relatively easy, being compatible with many of our current mobile phases - although best results were obtained with specific mixtures and different additives than what we commonly use (ammonium formate in pre-mixed solvent mixes instead of aqueous formic acid). Peak shapes OK, a little broad but in line with other polar separation columns we used in the past. Durability could be better, with columns failing/developing high pressures already after a few hundreds of samples."

"The XBridge is at high quality, it provides extremely good reproducibility, which is essential for bioanalytical analysis."

"One of column we received did not work well, but in general it's OK"

"We use this column with HPLC-fluorescence. We obtain reproducible chromatograms with this column. Waters was helpful in providing assistance for optimization and problem solving."

"High performance, meets the requirements for many applications, robust."

"I achieved good reproducibility of the results and ease of use."

"Using Waters products specially HPLC columns is a great experience, I hardly found any pressure issues or any kind of extra-unwanted peaks. It has great resolution. Thank you for providing a great product"

"Very robust column, has high efficiency and a long lifetime. Easy to use, in terms of before and after care and is easily fitted into all of our various LC systems."

"BEH Amide excellent HILIC column at various pH's. Great service from Waters."

"Nice separation of purine and pyrimidine compounds."

"I am using an C18 100x4.6mm column, with a particle size of 5µm. The column is very useful specially for single-component and fast methods, allowing you to an easy separation with a very short run time. The endurance of the column is beyond remarkable. At average conditions (pressure, column temperature) the column lasts for more than 10.000 injections, sometimes more than 20.000."

"Easy to work with simple column, last a long time."

"Robust column, reproducible results, long life time, in summary a column that you have to have in your lab."

"Results were great. Very reproducible and easy to use. I was highly satisfied with my Xbridge BEH C18. This is one of my go-to columns for analysis. The Waters team is there any time I have a question and respond quickly. Very satisfied customer."

"Easy to use. The column meets my expectations. Robustness"

"Easy to use and good reproductibility of the results even the samples are not always in the same buffer. Good experience."

"Easy to use, excellent reproducibility, more than 800 injections without bleeding or any changing"

"It was easy to use and passed all system suitability requirements. We are still currently using the same column for the same method."

"The column works very well for the application in our lab and several different people use it. We use it with eluents acetonitrile and 10 mM ammonium acetate in water at pH 9.2 for HILIC applications. Resolution is good, but we noticed when we try to increase ammonium acetate concentration, although apparently up to 20 mM should be okay, we loose resolution. Over time we found some background signal sticking to the column that is why we bought this new one. We would not use it without a guard, though. Equilibration of the column is straight forward and we got a good resolution and no background with the new column. Thus, really easy to use (well, we already knew the method we wanted to use) - it is all in the manual, although formulations could be written slightly easier, because for some parts we had to discuss whether we did get them right. I do not know what to comment on "after sales care", as I had not been contacted before, but the information before the purchase was good. Regarding the value for money, I understand that UHPLC columns in general are not cheap, so this analytical column is in a mid-price range. I would definitely recommend purchasing the guard with it, although I found it slightly annoying that you could only get it as a pack of three, which made it more expensive."

"Highly robust and reproducible results from these columns. Not ideal for all classes of metabolites as some peak shapes are very poor quality but the vast majority that we look for good shape and reproducible. We have seen this column successfully handle over 1700 injections"

"Gold standard for separation of oligos"

"It is easy to use, offers greater efficiency against traditional materials, although the cost is not exactly chear, it is worth the investment."

"After service from Waters is excellent. The column we purchased was very good. However, the resolution between peaks was did not meet our specification. That is why we returned the column."

"The column is robust and easy to use. I purchased a lot of Waters columns for my application. Really good products."

"The column performs very well. very good integration..I have not recieved any compliants."

"I've always been a big fan of XBridge columns. Their versatility across wide pH ranges and ruggedness to withstand thousands of injections is ideal for our fast paced CRO environment. High plate counts demonstrate great column efficiency allowing us the versatility to forgo UPLC applications. Column durability and applicability across highly variable analyte chemistries make Xbridge columns very attractive for our workflows."

"The Waters BEH XBridge XP is robust from column to column and from lot to lot. We are able to get consistent results that do not deviate from the test method parameters and are the expected results from method validation."

"High quality results, easy to use, excellent customer service."

"We have been achieving very high resolution with this column. True and transparent results. One thing about the guard column: it is not lasting long, after a few injections, we have to change the guard column. We had also tried using the column without the guard column and it lasted longer. Hence, guard column needs to be upgraded."

"We depend on the consistency of these columns for our analysis because of the minimal lot to lot variation. Retention times and column life are always consistent. Any small problem with an LC column has high impact on our lab which processes thousands of samples per day. Technical and customer support are above reproach, which gives us another level of confidence in Waters. The Bridge XP LC columns are first selected for method development by our Research and Development team because of their relatively high recovery, resolution and peak shape for most analytes."

"Great product and even better results. Thank you !!!"