TLC and HPTLC MS-Grade Plates by Merck

Manufacturer Merck  |  Available Worldwide
4.7
/
5.0
  |  2 reviews
Coupling TLC plates with mass spectrometry (TLC-MS) is a new field of high interest in planar chromatography. One particular advantage of TLC-MS is the flexibility it offers in the choice of mobile phases for separations. In comparison, HPLC-MS coupling does not allow the use of certain mobile phases, such as inorganic buffers.


TLC and HPTLC MS-Grade Plates by Merck product image
TLC and HPTLC MS-Grade Plates
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Average Rating: 4.7
2 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2021

  • Organization: Birlasoft



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Separation and Rf value is distinguishable
Rating: 4.3

  • Application Area: NCE characterization

"NCE at final step is separated with high resolution and easily visible. Product can be monitored during isolation and purification"

Review date: 02 Dec 2022 | TLC and HPTLC MS-Grade Plates
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Bangalore University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good plates very useful in the pharmaceutical industry
Rating: 5.0

  • Application Area:Separation of plant samples

"TLC plates are useful for the separation of compounds from crude extract. Used in forensic science and the synthesis of plant based products."

Review date: 11 Feb 2022 | TLC and HPTLC MS-Grade Plates

Several combinations of TLC with MS are possible: Elution-based TLC-MS or desorption based TLC-MS. We offer TLC-MS plates as well as HPTLC-MS on Glass or alumina backing to meet the individual need of our customers.

  • TLC-MS Coupling Techniques: The techniques for coupling TLC with mass spectrometry can be divided into elution-based, or desorption-based. Both approaches are offline, and are performed after the separation is completed and the plate dried. Sample transfer to the mass spectrometer is fast and typically takes less than one minute.
  • Elution-based TLC-MS: The analyte on the silica plate is dissolved in a solvent and transferred to the mass spectrometer in the liquid phase. In addition the combination to many other analytical methods are possible including eluting the selected band into vials for further investigation
  • Desorption-based TLC-MS: The analyte is vaporized from the silica, and transferred to the mass spectrometer in the gas phase. Vaporization techniques include gas beam, ion bombardment, and MALDI (matrix-assisted laser desorption/ionization).

Product Overview

TLC and HPTLC MS-Grade Plates by Merck product image

TLC and HPTLC MS-Grade Plates

Manufacturer Merck  |  Available Worldwide

4.7 / 5.0 | 2 reviews