StreamSelect LC/MS System
LC/MS/MS is ideally suited for direct, rapid analysis of prepared biological samples. In high-throughput analytical environments , sample analysis times can be shortened by optimizing LC gradient, flow rate or column. A greater gain in throughput can be achieved by limiting the MS acquisition time to the portion where compounds of interest are eluted.
Good companion to the analytical team.
Analysis of materials and intermediates
Ease of use. Versatile. Better samples throughput efficiency. Reproducible results.
Review Date: 27 Oct 2018 | Agilent Technologies
LC/MS/MS is ideally suited for direct, rapid analysis of prepared biological samples. In high-throughput analytical environments , sample analysis times can be shortened by optimizing LC gradient, flow rate or column. A greater gain in throughput can be achieved by limiting the MS acquisition time to the portion where compounds of interest are eluted.
The fully integrated Agilent StreamSelect LC/MS system increases throughput with minimal user interaction. Intelligent software automatically coordinates staggered injections from four 1200 Infinity Series HPLC systems connected in parallel to a single triple quadrupole instrument. The ability of the StreamSelect LC/MS system to run robust and reliable parallel chromatographic separations with optimized MS output greatly enhances sample throughput and lab productivity.
Use this online cost calculator to see what your return on investment could be with the StreamSelect LC/MS system.
Features:
- Up to 4-fold increase in sample throughput via efficient scheduling of mass spectrometer acquisition time
- Optional online trap-end-elute sample clean-up capability further reduces total turn-around time.
- Intelligent automation software controls the fully integrated StreamSelect LC/MS system with minimal user input and no dropped samples
- Fast, high resolution chromatography with the 1200 Infinity Series LC system results in high data quality
- Coupling with 6400 Series triple quadrupole LC/MS system delivers superior sensitivity and renowned performance reliability
- Expert support from Agilent team ensures fast implementation into a high-throughput LC/MS laboratory
Brochures
StreamSelect brochure: Produce results up to 4x faster
Are you struggling to meet the challenges of increased sample volumes and shorter turnaround times? Can you benefit from a system that offers easy adoption and even easier method development? Do you want to maximize your LC/MS investment? This product brochure demonstrates the features and benefits of the Agilent StreamSelect system.
Analysis of cannabinoids and their metabolites in urine using the MassHunter StreamSelect LC/MS system
This application note by Agilent describes a highly selective analytical method developed for the analysis of six cannabinoids using liquid chromatography with triple quadrupole mass spectrometry (LC/MS/MS).
Analytical development of a four‑stream multiplexed LC/MS method for the simultaneous determination of SDMA and ADMA
This application note by Agilent demonstrates the development and confirmation of an analytical method for asymmetric and symmetric dimethyl arginine (ADMA and SDMA respectively).
The Agilent StreamSelect LC/MS solution: Increasing the throughput of a triple quadrupole mass spectrometer
This technical overview by Agilent illustrates the advantages of the StreamSelect LC/MS solution design for boosting lab productivity using innovative fl ow path design and software control to assure effi cient and reliable operation.
Webinar slides: Expand your laboratory capabilities with the Agilent StreamSelect LC/MS system
Download the accompanying slides to the SelectScience webinar: Expand your laboratory capabilities with the Agilent StreamSelect LC/MS system. During this webinar, Ryan J Rademacher, the Clinical LCMS and StreamSelect product manager, and Kevin McCann, a StreamSelect and RapidFire product owner, describe how the Agilent StreamSelect LC/MS system increases reliability and productivity. Watch the webinar here.
Enhance lab productivity with Agilent automation solutions
Lab productivity is facing significant challenges, including rising demand, staffing shortages, and the need to maintain data quality while achieving high throughput. Discover how Agilent Technologies is transforming lab productivity with advanced automation solutions. In this video, Agilent Technologies’ Senior Product Managers Thomas Wu and Kevin McCann introduce the Bravo liquid handling platform and high-throughput mass spectrometry solutions such as the StreamSelect LC/MS System and RapidFire High Throughput MS. Learn how Agilent’s automation technologies help scientists enhance efficiency, reliability, and scalability in life sciences and genomic applications.
This video was filmed at SLAS2025.
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Expand your laboratory capabilities with the Agilent StreamSelect LC/MS system: Your questions answered
Watch this on-demand webinar to find out how to use the Agilent StreamSelect LC/MS system to increase throughput in your laboratory
Expand your laboratory capabilities with the Agilent StreamSelect LC/MS system
Watch this webinar to find out how to use the Agilent StreamSelect LC/MS system to increase throughput in your laboratory
Top methods and technologies advancing the field of mass spectrometry
Explore exclusive interviews, methods, and free downloads to help you optimize your mass spectrometry experiments
How to multiplex up to 4 liquid chromatography systems with StreamSelect technology – your questions answered
Watch our on-demand webinar to learn how to expand your lab capabilities with this mass spectroscopy technology


























