STEMdiff™ APEL™ 2 Medium is a fully defined, serum-free and animal component-free medium for the differentiation of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells. It is based on the APEL formulation published by Dr. Andrew Elefanty and lacks undefined components such as protein-free hybridoma medium.
STEMdiff™ APEL™ 2 can be used in adherent or embryoid body (EB)-based protocols, such as with AggreWell™. It can be used with a variety of different induction factors or cytokines to support differentiation along ectoderm, mesoderm and endoderm lineages.