Member since: 2017
Organization: Waynesburg University
Great instrument for crystal detection
Application Area: Protein and APIs crystallinity detection
"The signal to noise ratio is very high for this second harmonic generation microscopy. And the use of this system is straight forward. But the beampath needs to be realigned sometimes."
SONICC® provides users the ability to:
Two powerful technologies, Second Harmonic Generation (SHG) and Ultraviolet Two-Photon Excited Fluorescence (UV-TPEF) are combined in a completely automated imager to quickly image your high throughput crystallization plates and positively identify protein crystals. Crystals appear white against a stark black background, helping you to identify crystals even in murky environments. SONICC can detect extremely thin crystals, microcrystals <1 μm, and crystals obscured in birefringent LCP.
Major pharmaceutical and academic research labs worldwide find SONICC to be extremely successful, cost-effective, and efficient.