Resolvin D1 by Cayman Chemical Co.

Manufacturer Cayman Chemical Co.
4.7
/
5.0
  |  1 reviews
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase. A 17(R)-epimer (Item No. 13060) of RvD1 can also be generated in aspirin-treated ... Read more


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Resolvin D1
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Average Rating: 4.7
1 Scientist has reviewed this product

4 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2021

  • Organization: University of Tennessee HSC



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great resolvin D1.
Rating: 4.7

  • Application Area: Protein levels

"Resolvin D1 is a very good product. Its activity is very high in cells."

Review date: 19 Mar 2021 | Resolvin D1

Manufacturer's Response

Raj, we are happy to hear about your positive experience. Thank you for taking the time to leave a review.

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. 90110) and docosahexaenoic acid (DHA; Item No. 90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase. A 17(R)-epimer (Item No. 13060) of RvD1 can also be generated in aspirin-treated samples. Both RvD1 and its 17(R)-configuration reduce human polymorphonuclear leukocyte (PMNL) transendothelial migration, the earliest event in acute inflammation, with EC50 values of ~30 nM. RvD1 and its aspirin-triggered form also exhibit a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with a maximal inhibition of ~35% at a 10-100 ng dose. Analytical and biological comparisons of synthetic RvD1 with endogenously derived RvD1 have confirmed its identity as matching the natural product.

Product Overview

Resolvin D1 by Cayman Chemical Co. product image

Resolvin D1

Manufacturer Cayman Chemical Co.

4.7 / 5.0 | 1 reviews