Member since: 2017
Organization: Mabtech AB
We use the Octet RED384 because it is accurate, fast and easy to work with.
Application Area: Optimize selection of new antibody producing cells
"We use the Octet RED384 system to help optimize the selection of new antibody producing cells. The way the Octet RED384 uses Bio-Layer Interferometry (BLI) allows for binding assays to be conducted without having to label the antibody or antigen, and can be performed on supernatant level, being a great advantage for us compared to traditional and time consuming ELISAs."
Member since: 2008
Organization: Ablynx S.A.
Nice device which is perfect for epitope binning and obtaining kinetics quickly
Application Area:Kinetics and epitope binning
"The Octet RED384 can quickly generate a lot of data. The sensitivity appears to be lower than SPR platforms nevertheless it is worthwhile to consider since the sensors are significantly cheaper and data can be generated very fast."
The system provides analytical performance similar to the 8- channel Octet RED96 system, but with higher levels of throughput, speed, and flexibility.
The high detection sensitivity and impressive throughput of Octet RED384 system has made it a favorite for small molecule library screening and analysis of large cross-competition binding matrices.
Kinetic analysis including association and dissociation of biomolecules can be performed on up to 384 samples in one 384-well microplate. Fully automated workflows can be realized due to integrated robotic solutions. Target ligands can be batch immobilized onto biosensors and returned to the biosensor tray for re-use in future experiments, thus extending the number of uses for each biosensor, preserving valuable ligand, and maximizing flexibility in experimental design.
- Sensitivity – Detection of low molecular weight molecules (≥ 150 Da)
- High throughput – 16-well simultaneous sampling in 384-well and 96-well formats
- Flexibility – Two plate locations maximize throughput and improve workflow
- Unattended operation – Automation friendliness allows multiple-plate assays in one run
- User friendliness – Advanced software offers greater versatility in experimental design and data analysis