Products & ReviewLife Sciences

Octet® R4 BLI System

Sartorius GroupAvailable: Worldwide

Affordable and Flexible Biologics Development 

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Description

The Octet® R4 System is priced for customers looking for a balance between throughput and cost. This system provides higher throughput than the 2-channel Octet® R2 instrument, and the same sensitivity as the 8-channel Octet® R8 instrument - at a lower overall price.
Key benefits:

  • Fast Results - The Octet® R4 system has four parallel, independent channels for increased flexibility and faster results.
  • High Sensitivity, Moderate Throughput, Low Cost - The Octet® R4 system is designed for customers looking for moderate throughput sample analysis, without any compromise on assay sensitivity.
  • Reduced Assay Time and Maintenance Cost - The Octet® platform provides faster time to results and process economy when compared to other technologies due to its fluidics-free Dip and Read format. Additionally, crude sample compatibility saves valuable time by eliminating the need for sample pre-treatment, and non-destructive testing conserves precious samples for other assays.
  • Field Upgradeable within a Single Visit - Choose when to upgrade to an 8-channel Octet® system for higher throughput and full GMP compliance. Upgrades are performed on-site within a single visit by trained Sartorius engineers without the hassle of down time or system trade-in.

Small molecule binding kinetics

This application note describes the method setup process for a successful protein-small molecule binding interactions analysis on Octet® R2, R4, R8, RH16, and RH96 instruments. Discover tips on best practices for the preparation of optimal reagents for small molecule binding studies and data analysis including data referencing procedures.


Application NoteLife Sciences

Octet Systems: Superior performance, unrivaled flexibility

Your research should be guided by your imagination, not by the limitations of your label-free system. In this brochure, Sartorius introduces the Octet® platform's, with flexible, open-format design and comprehensive menu of biosensors letting you attack research challenges in unique new ways.



Accelerate assay development and reduce cycle times for AAV quantification in complex biological samples

Assessing AAV vector quality in gene therapy manufacturing is crucial, but the current gold standard, serotype-specific ELISA, has its drawbacks — time-consuming and prone to matrix effects. In this webinar, Dr. Yoann Saucereau from ExcellGene reveals how a label-free approach not only cut down on complexities in biological matrices but also enabled a quick, routine method. Now, ExcellGene effortlessly analyzes up to 96 samples in under 30 minutes for efficient AAV platform development.

Key learning objectives

  • Explore how suitable QC workflows are established in AAV development and manufacturing
  • Discover the critical role of assay design and development to determine correct binding kinetics, affinity values or analyte concentrations
  • Consider the optimization and evaluation of an AAV titer assay in comparison to Octet® AAVX Biosensors

Who should attend?

  • Lab researchers

Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.


Octet BLI solutions: Part 2 – Instruments

The Sartorius Octet® bio-layer interferometry (BLI) system allows researchers to analysis protein-protein and protein-small molecule interactions. In this video, Sartorius introduces the Octet® R series that provides a modular and scalable solution for molecular screening in 96-well microplates.


Octet BLI solutions: Part 3 – Applications

In this video, Sartorius demonstrates the range of applications bio-layer interferometry (BLI) has in biomolecular analysis workflows and the drug discovery pipeline, including the benefits of the Octet® BLI systems across the entire workflow.


Octet BLI solution: Part 1 – Technology

In this video, Sartorius presents the evolution of the Octet® bio-layer interferometry (BLI) system, providing researchers with a label-free approach to monitoring biomolecular interactions, for over 15 years.


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