Multi-MPS 12 (T12) Consumable Plates by CN Bio

Manufacturer CN Bio
MPS-T12 consumable plates from CN Bio are used to culture advanced 3D in vitro single or multi-organ-on-chip barrier models under perfusion, such as gut-on-a-chip, gut-liver, lung-on-a-chip or lung-liver, to generate clinically translatable data.


Multi-MPS 12 (T12) Consumable Plates by CN Bio product image
Multi-MPS 12 (T12) Consumable Plates
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In conjunction with the PhysioMimix OOC lab-benchtop ready microphysiological (MPS) system, MPS-T12 consumable plates are used to culture advanced 3D in vitro organ-a-chip models that provide fast, accurate and clinically translatable human data for improving the predictability of drug discovery.

The MPS-T12 consumable plate is designed for single or multi-organ-on-chip barrier model studies. It features 12 independent wells that are compatible with standard 24-well plate 0.33 cm2 Transwell® inserts.

MPS-T12 consumable plates provide novel insights into the effects of flow on organ cultures grown on Transwell® inserts, or dual organ crosstalk. Dual organ crosstalk studies are achieved subjecting an organ tissue grown on the Transwell® to continual perfusion in the presence of a second tissue type that is cultured on an insert located at the base of the well. Example co-culture studies such as gut-liver, lung-liver, brain-liver or skin-liver assays.

Validated applications for T12 plates include:

  • ADME (Drug metabolism and absorption)
  • PK/PD
  • Genotoxicity
  • Immune interactions

MPS-T12 consumable plates are: 

  • Suitable for organoids, spheroids, iPSCs, primary cells, immortalized cell lines and commercial inserts (such as MucilAir® or EpiSkin©)
  • For sole use with CN Bio’s PhysioMimix OOC lab-benchtop ready microphysiological (MPS) system. 
  • Designed to support users transitioning from 2D cell culture into 3D microtissues via a familiar open-well plate-based format 
  • PDMS-free, reducing non-specific binding for non-biased assessment of drug responses 
  • Compatible with standard 24-Transwell® 

Contact CN Bio for more information about 3D in vitro models validated using MPS-T12 consumable plates, or guidance designing your own bespoke tissue or organ mimics. 
 

Product Overview

Multi-MPS 12 (T12) Consumable Plates by CN Bio product image

Multi-MPS 12 (T12) Consumable Plates

Manufacturer CN Bio

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