In conjunction with the PhysioMimix™ OOC lab-benchtop ready microphysiological (MPS) system, MPS-T12 consumable plates are used to culture advanced 3D in vitro organ-a-chip models that provide fast, accurate and clinically translatable human data for improving the predictability of drug discovery.
The MPS-T12 consumable plate is designed for single or multi-organ-on-chip barrier model studies. It features 12 independent wells that are compatible with standard 24-well plate 0.33 cm2 Transwell® inserts.
MPS-T12 consumable plates provide novel insights into the effects of flow on organ cultures grown on Transwell® inserts, or dual organ crosstalk. Dual organ crosstalk studies are achieved subjecting an organ tissue grown on the Transwell® to continual perfusion in the presence of a second tissue type that is cultured on an insert located at the base of the well. Example co-culture studies such as gut-liver, lung-liver, brain-liver or skin-liver assays.
Validated applications for T12 plates include:
MPS-T12 consumable plates are:
Contact CN Bio for more information about 3D in vitro models validated using MPS-T12 consumable plates, or guidance designing your own bespoke tissue or organ mimics.