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Status:
Reviewer
Member since: 2019
Organization: The University of Sydney
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- Ease of use
- After sales service
- Value for money
Great for homogenous powdering of tissue samples whilst frozen.
Application Area: Homogenising mouse tissue samples - dry or lysis
"We have been using the Retsch MixerMill 400 to dry grind our mouse tissue samples while keeping them cold. This machine has allowed us to finely grind the tissue to a powder while keeping the samples frozen and then aliquot the homogenous powder for multiple downstream uses. The racks can be prechilled in a liquid nitrogen bath, removed for grinding and then straight back onto liquid nitrogen to keep the samples frozen. We can do 20 x 2mL tubes at one time substantially saving us time compared to hand grinding one by one. Additionally, we have used this for several lysis protocols including lysing in phenol for RNA extraction and into lysis buffers for protein analysis."
Review date: 05 Dec 2019 | Mixer Mill MM 400
Status:
Reviewer Member since: 2017
Organization: IZO s.r.l. a socio unico
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- Ease of use
- After sales service
- Value for money
Good results, easy to use.
Application Area:Sample homogenization
"The mixer mill Retsch MM 400 is a compact bench-top unit, which has been developed specially for grinding or milling of small amounts of sample. It can mix and homogenize powders and suspensions or disrupt biological cells as well as for DNA/RNA and protein extraction."
Review date: 15 May 2017 | Mixer Mill MM 400
The mixer mill MM 400 is a compact versatile bench-top unit, which has been developed specially for dry, wet and cryogenic grinding of small amounts of sample.
It can mix and homogenize powders and suspensions in only a few seconds. It is also perfectly suitable for the disruption of biological cells as well as for DNA/RNA and protein extraction. With its high performance and great flexibility the mixer mill MM 400 is a unique product in the market.
You may also be interested in the High Energy Ball Mill Emax, an entirely new type of mill for high energy input. The unique combination of high friction and impact results in extremely fine particles within the shortest amount of time.
Advantages:
- Reproducible, efficient grinding, mixing and homogenization in seconds
- Powerful grinding by impact and friction, up to 30 Hz for up to 20 samples per run
- 3 different grinding modes (dry, wet or cryogenic)
- Screw-top grinding jars for leak-proof grinding
- 9 SOPs can be stored
- Wide range of accessories including various jar and ball sizes, adapter racks for single use vials and tubes, grinding tool materials, CryoKit
- Efficient cell disruption of max. 240 ml cell suspension for DNA/RNA- and protein extraction
- Isolation of bacteria from tissue in 8 x 30 ml bottles or 10 x 5 ml vials for accurate diagnosis of infections
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