Fast and Reproducible Method for Cell Disruption

20 Apr 2015

A very efficient method of cell disruption is bead beating, where cells in suspension are mechanically disrupted by glass beads in single use reaction vials. In this application note, the RETSCH Mixer Mill MM 400 in combination with the Falcon tube adapter is used to make the cell disruption process reproducible, fast and efficient. The effectiveness of the method is demonstrated using examples of cell disruption of yeast cells (Saccharomyces cerevisiae) and microalgae cells (Thalassiosira pseudonana and Phaeodactylum tricornutum).

Mixer Mill MM 400

Retsch GmbH

The mixer mill MM 400 is a compact versatile bench-top unit, which has been developed specially for dry, wet and cryogenic grinding of small amounts of sample.

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Fast and Reproducible Method for Cell Disruption