ResourceGeneral Lab

Process reliability in pharmaceutical research and production

27 May 2026

This application note outlines how advanced milling and air jet sieving technologies support process reliability in pharmaceutical research and production. It highlights the importance of precise particle size control in drug development, formulation, and quality assurance, and demonstrates how integrated workflows can improve reproducibility, efficiency, and compliance with GMP requirements. The resource also explores scalable approaches to co-crystal screening and production, from laboratory studies to kilogram-scale manufacturing.

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Mills, Sieves and PressesMills, sieves and presses are used to break and sort solid materials into smaller particle sizes for further processing such as pellet pressing or analysis. Milling equipment includes grinders, ball mills, cutting mills, jaw crushers, knife mills, beater and planetary mills. Sorting of smaller particulates can be achieved with test sieves and sieve shakers. Final powders can be pressed with hydraulic presses. Milling and pressing solid samples is an important preparation step in X-ray fluorescence spectroscopy (XRF) and diffraction (XRD). Find the best mills, sieves and presses in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Process DevelopmentProcess development aims to optimize the performance of manufacturing systems. This involves the assessment of quality and efficiency of both processes and products. This is particularly important in the scale-up of chemical processes.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria. Particle Analysis