MaxPeak premier SEC columns
Size-based separations of peptides, proteins, and viral vectors
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Get unmatched batch-to-batch reproducibility with the wide range of Waters Size-Exclusion Chromatography (SEC) Columns and standards for protein and peptide characterization.
SEC is a powerful technique for aggregate and fragment analysis in the research, development, and manufacturing of biotherapeutic proteins, such as insulin and monoclonal antibodies (mAb). With SEC, also known as gel filtration, you can separate proteins based on their size (hydrodynamic radii versus absolute molecular weight) in solution, with larger sized species eluting before smaller proteins.
The pore size and volume of the SEC particles used in the packed column drives this isocratic based technique, so the column you choose matters. As the molecular weight of the proteins of interest increases, SEC columns with comparatively larger pore size particles are selected.
Analytical workflow solutions for PFAS analyses
Environmental contamination by per- and polyfluoroalkyl substances (PFAS) and rising concerns about its long-term impacts on the general population, have increased the urgency for wider PFAS analysis. Initially the focus was solely on environmental matrices but has now expanded into food analysis due to the risk to consumers. Accordingly, regulations and guidance documents have been released to assure the quality of water bodies, drinking water and most recently also for food and feed. Here, Waters describes the workflow of its sample-to-result approach for PFAS analysis that can be incorporated into any lab whether the focus is food, water or environmental.
Why researchers turn to reversed phase chromatography when purifying GLP-1
Tuesday, April 28 at 16:00 BST | 17:00 CEST | 11:00 EDT | 08:00 PDT
Purifying synthetic peptides is a critical step in developing advanced biotherapeutics like GLP-1 receptor agonists. Even with precise synthesis, impurities such as deletions, truncations, and chemical modifications are unavoidable, making purification essential for achieving high purity, optimal yield, and cost efficiency.
Join this SelectScience® webinar to discover why reversed-phase chromatography (RP) remains the gold standard for peptide purification and analysis. This session will be led by Bill Warren, Principal Consultant Product Manager, Waters Corporation, who has extensive experience with chromatography techniques for protein purification. He will guide you through the complete lab-scale purification process for a GLP-1 RA using optical detection, and will show how these strategies can be applied to other synthetic peptide modalities, including radio-labeled peptides, cyclic peptides, peptide antimicrobials, and more.
Key learning objectives:
- Understand strategies for developing analytical scale biotherapeutic peptide separations.
- Learn techniques for lab-scale preparative synthetic peptide separations and fraction analysis.
- Explore how reversed-phase mobile phase modifiers and chemistries impact peptide separation performance.
- Gain practical troubleshooting tips for reversed-phase peptide separations.
Who should attend?
- Biopharmaceutical and peptide research professionals, including academics and industry scientists.
- Biopharma outsourcing partners, such as CDMOs, CMOs, and CROs.
- Broader biopharmaceutical industry professionals involved in development, manufacturing, or research.
Certificate of attendance
If you attend the live webinar, you will automatically receive a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
If you view the on-demand webinar, you can request a certificate of attendance by emailing editor@selectscience.net.
Webinar details
- Cost: Free to attend
- Location: Online
- Duration: 60 minutes
Registration is required to secure your place. If you register but can’t attend live, you will receive a link to the on‑demand recording once it becomes available.
