Infinium MethylationEPIC Kit
Robust methylation profiling microarray with unparalleled coverage of CpG islands, genes, and enhancers. Use for epigenome-wide association studies.
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Comprehensive Genome-Wide Coverage
DNA methylation sites (human) at single nucleotide resolution
Interrogate over 850,000 DNA methylation sites (human) at single-nucleotide resolution. Sodium bisulfite conversion of DNA is the fastest, easiest, and most popular way to study DNA methylation analysis and selecting the right bisulfite conversion kit can be the difference between accurate data and frustrating wasted hours spent in the lab. Choosing a bisulfite conversion kit is an important step in DNA methylation studies to ensure that you obtain the highest quality bisulfite-converted DNA possible going into downstream applications. Multiple samples, including FFPE, can be analyzed in parallel to deliver high-throughput power while minimizing the cost per sample.
Review Date: 23 May 2022 | Illumina
Good Chip with reasonable cost:results ratio.
Epigenetics
Infinium® MethylationEPIC BeadChip permits more methylation signals so we have a better picture of epigenetic processes in different NCDs.
Review Date: 17 Apr 2018 | Illumina
Product Highlights
With the Infinium MethylationEPIC BeadChip Kit, researchers can interrogate over 850,000 methylation sites quantitatively across the genome at single-nucleotide resolution. Multiple samples, including FFPE, can be analyzed in parallel to deliver high-throughput power while minimizing the cost per sample.
Infinium HD array technology enables content selection independent of bias-associated limitations often associated with methylated DNA capture methods. The result is a pan-enhancer and coding region view of the methylome that can be used for epigenome-wide association studies on a variety of human tissues.
Comprehensive Genome-Wide Coverage
This kit includes the following content categories requested by methylation experts:
- CpG sites outside of CpG islands
- Non-CpG methylated sites identified in human stem cells (CHH sites)
- Differentially methylated sites identified in tumor versus normal
- FANTOM5 enhancers
- ENCODE open chromatin and enhancers
- DNase hypersensitive sites
- miRNA promoter regions
- > 90% of content contained on the Illumina HumanMethylation450K BeadChip
