Member since: 2021
Organization: UMR 1227 - LBAI
Great results, but need time for analyses
Application Area: Analyze tumor microenvironment
"The automat has been used for the exploration of the tumoral microenvironment of tumoral and inflammatory colon and gastric tissues. Acquisitions take a bit of time, but it is quite easy to use the automat. The longest part is to make the preparation work for the antibodies panel and the tissues, and the most difficult part is the analysis of the huge amount of data generated by Hyperion."
Changing the course of how diseases are treated and ultimately cured requires a comprehensive understanding of complex cellular phenotypes and their interrelationships in the spatial context of the tissue microenvironment. Imaging Mass Cytometry™ (IMC™) performed on the Hyperion™ Imaging System using Maxpar® metal-tagged antibodies empowers simultaneous imaging of up to 37 protein markers imaged at a time. Bringing together high-parameter CyTOF® technology with imaging capability, the Hyperion Imaging System enables deep interrogation of tissues and tumors at subcellular resolution to uncover pathology insights, new biomarker correlations and cell interactions.