DNA Clean & Concentrator™-25 by Zymo Research

Manufacturer Zymo Research  |   Model: D4005
4.8
/
5.0
  |  20 reviews
The DNA Clean & Concentrator™-25 cleans and concentrates up to 25 µg of DNA in as little as 2 minutes.


DNA Clean & Concentrator™-25 by Zymo Research product image
DNA Clean & Concentrator-25 Kit
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Average Rating: 4.8
20 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2020

  • Organization: University of Washington



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Awesome.
Rating: 5.0

  • Application Area: Plasmid clean up

"So great for concentrating to 6ul, use often for illumina library prep."

Review date: 04 Dec 2020 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: University of California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great! Reliable and best on the market.
Rating: 5.0

  • Application Area:Cleaning PCR up for cloning reactions

"The DNA cleanup kit from Zymo is wonderful to clean up PCR products for downstream cloning. Never had a problem with the kit and is better than common "premium" cleanup kits I've used. Will be using this product for a long time, it's so reliable!"

Review date: 05 Jun 2020 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: University of Connecticut



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Useful and reliable for single-cell extraction.
Rating: 5.0

  • Application Area:Single-cell DNA extraction for PCR

"We work with single-celled marine organisms (ciliates) and it can be difficult (a) to extract ample DNA for downstream PCR application and (b) to eliminate PCR inhibitors present in seawater (ex. seawater itself, to start). We've played around and purchased a lot of different DNA extraction kits and this (and the 5 kit) are the only to reliably extraction ample DNA for PCR amplification."

Review date: 05 Jun 2020 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Iowa State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Simple to use, saves so much time!
Rating: 5.0

  • Application Area:PCR purification of DNA fragments

"Compared to other PCR cleanup kits, this saves so much time and results in much concentrated samples. It allows elation in very small volumes."

Review date: 16 Dec 2019 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Instituto Tecnologico de Costa Rica



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Cost effective, easy to use, and great results!
Rating: 5.0

  • Application Area:gDNA library preparation (restriction digest cleaning, sample pooling, library cleaning)

"DNA cleaning is a must during ddRAD library preparation. The kit provides an easy way to eliminate enzymes and by-products after the restriction digest and barcode adapter binding steps or after PCR. I prefer this kit much more than using magnetic beads. This kit is cheaper and just works. You don't have to mess with beads or buffer concentration, nor buy expensive magnetic plates. As a side note, I work with plant tissue, sometimes do to latex, resins, and phenolic compounds – so DNA extraction and purification can be a hassle. Furthermore, depending on the source material (leaf, bark, root, etc...), DNA yield can vary widely. Using this kit has proven to be a cost effective and easy way to clean and concentrate samples, regardless of DNA extraction protocol and source material. DNA recovery from the columns is quite good, with minimal losses after cleaning (based on Nanodrop readings before and after)."

Review date: 11 Dec 2019 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: UNC Biospecimen Processing Facility



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    1 out of 5
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Lost precious samples due to degradation of the spin columns.
Rating: 3.3

  • Application Area:Concentration of genomic DNA samples.

"We have not used this kit since 2018 due to the following problems with the Zymo-Spin IIC-XL, which were observed multiple times with multiple lots. Customer service and Zymo techs were very helpful but the processing issue was never resolved. After processing our samples with the Zymo kit, there is a significant decline in the 260/280 and 260/230 values. A white, heterogeneous residue is visible when transferring the eluent from the final collection tube to a 1.5ml screwcap tube. A small, white pellet is visible if samples are spun for 5 minutes at 16,000g. Once the supernatant is removed from the pellet, only slight improvement is observed – and the 260/280 and 260/230 values are still significantly lower than pre-Zymo values. It seems like the spin column filter is degrading and coming through with the eluent. We were unable to continue processing any samples using the Zymo gDNA Clean & Concentrator Kit, as we cannot afford to lose precious sample."

Review date: 02 Dec 2019 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Northwestern



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great!
Rating: 5.0

  • Application Area:Clean sample during smFISH probe production

"The instructions are simple and easy to follow. The company is willing to help with any issues with the product. I feel that the amount of reagent and materials in the kit is cost effective."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Icahn School of Medicine at Mount Sinai



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great results and critical to our research.
Rating: 4.7

  • Application Area:Clean up DNA following isolation from blood samples, for future use in DNA methylation analyses

"I regularly achieve high quality results with this product! Any inability to achieve DNA at the end of my concentrating is likely due to errors along the first isolation step attributed to a kit outside of Zymo Research. The kit is very easy to use and great value!"

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Illinois



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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I will keep using it.
Rating: 5.0

  • Application Area:Vector construction

"This is my to-go kit for cleaning DNA for different applications. it is straightforward and consistent. It is also very affordable compared to similar products from other brands."

Review date: 05 Jun 2019 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Georgia Institute of Technology



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very easy to use with good results.
Rating: 5.0

  • Application Area:Concentrate DNA for PCR

"I have been using the product for a year now. Very easy to use with good results. Highly recommended!"

Review date: 28 Jul 2016 | DNA Clean & Concentrator™-25


  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Pomona College



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Good for concentration into small volumes.
Rating: 4.3

  • Application Area:Clean and concentrate DNA following PCR or Gibson Assembly

"Useful for concentrating DNA product into small volumes (such as for transformation), but showed greater loss of product in direct comparison with other DNA concentration products in my lab."

Review date: 28 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: OHSU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to use, reproducible results and an essential lab kit.
Rating: 5.0

  • Application Area:Clean and concentrate DNA samples

"Zymo Clean and Concentrator kit yields reproducible results and is extremely quick. I don't notice a yield loss when adding a sample to this column in order to exchange buffers or concentrate my DNA samples."

Review date: 21 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of California, San Diego



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great kit, easy to use, and everyone in the lab uses it.
Rating: 5.0

  • Application Area:DNA cloning, PCR cleanup, primer removal.

"The kit is easy to use and gives consistent results. Useful for cloning and other molecular biology applications. Good to concentrate DNA with elution in small volumes."

Review date: 20 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: UT Austin



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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It does the job it says it can.
Rating: 4.7

  • Application Area:I use this kit to concentrate and clean up PCR for genome engineering purposes.

"Excellent value kit to concentrate your sample. It is effective and usually gives high yields."

Review date: 14 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Michigan State Univeristy



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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For the price and ease, it’s great to work with.
Rating: 4.3

  • Application Area:Clean and concentrate DNA after extraction from human tissues

"The product is very easy to use. The best part is able to elute in small volumes which is very beneficial. The only caveat is the loss after clean up. I have experienced 40-50% loss and would like more recovery. DNA has been used for downstream applications such as bisulfite analysis and exome sequencing and the data was very clean."

Review date: 13 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Duke University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Works really well -- I suggest this over other clean-up kits.
Rating: 5.0

  • Application Area:DNA purification after restriction digest

"The clean and concentrator kit is simple to use, with quick-to-use instructions included in the box. Cleaning up the DNA takes <7 minutes from addition to the column to elution. The best part is being able to control the volume of elution from the column, with 6 µL the minimum! Now I can get concentrated DNA to use for in vitro transcription."

Review date: 13 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Singlera



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very easy to use with high recovery
Rating: 5.0

  • Application Area:Purification of dna

"Very easy to purify DNA for ngs. High quality results with great recovery. I would recommend this kit over other columns"

Review date: 13 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Connecticut



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Love Zymo kits, they are my favorite.
Rating: 5.0

  • Application Area:Clean DNA for PCR and sequencing

"Zymo products are great. The kits have easy workflows and are well organized when shipped. The protocols are also nice and simple to follow and if I ever have any questions, the support staff is very helpful."

Review date: 12 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Lineberger Comprehensive Cancer Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Nice results overall
Rating: 5.0

  • Application Area:DNA purification from enzymatic reaction

"Its gives high yield and its pretty easy to use and need very less time."

Review date: 12 Jul 2016 | DNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Yale



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Love this product!
Rating: 4.7

  • Application Area:cloning of bacterial expression constructs

"This is a wonderful product! Easy to use and produces great results each time!"

Review date: 11 Jul 2016 | DNA Clean & Concentrator™-25

The DNA Clean & Concentrator™-25 (DCC™-25) is designed for rapid desalting and purification of up to 25 µg DNA from enzymatic reactions (e.g., PCR), endonuclease digestions, or cell-free lysates.

Simply add the specially formulated DNA Binding Buffer to your sample and transfer to the supplied Zymo-Spin™ column.

The product features Fast-Spin column technology to yield high-quality, purified DNA in just minutes, and it is compatible with cDNA and ssDNA. Eluted DNA is suitable for sequencing, microarray analysis, PCR, nucleotide blotting, and restriction endonuclease digestion procedures.

Product Overview

DNA Clean & Concentrator™-25 by Zymo Research product image

DNA Clean & Concentrator™-25

Manufacturer Zymo Research

4.8 / 5.0 | 20 reviews