Direct-zol™ RNA Microprep by Zymo Research

Manufacturer Zymo Research  |   Model: R2060  |  Available Worldwide
4.9
/
5.0
  |  26 reviews
Total RNA and small/miRNA from TRIzol without phase separation


Direct-zol™ RNA Microprep by Zymo Research product image
Direct-zol RNA Microprep Kits
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Average Rating: 4.9
26 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2021

  • Organization: UT Southwestern medical center dallas



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fantastic cost effective high quality RNA from small number cells or tissue
Rating: 5.0

  • Application Area: RNA from small sample

"High quality RNA from small number of cultured cells or tissue. We were using the Arcturus picopure kit and it was 10$ per sample to prep. This kit provides faster and easier protocol that costs less than a. 1/3 the price. 3$ per sample. Love this kit!"

Review date: 07 Jun 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of the Sciences



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Quick workflow without compromising on quality.
Rating: 5.0

  • Application Area:RNA isolation

"This kit gets me high quality RNA at a cheap price and quick flow-through. Bare minimum of your own supply/equipment needed, most things come in the box."

Review date: 26 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2017

  • Organization: University of Minnesota Medical School



  • Ease of use
    5 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
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The kits are our go to for RNA extraction.
Rating: 4.0

  • Application Area:Real time PCR

"This has been a game changer as we have been accustomed to using Qiagen kits until recently."

Review date: 26 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results, will keep using it.
Rating: 5.0

  • Application Area:RNA extraction

"Easy to use and great RNA quality."

Review date: 26 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Texas Health at San Antonio



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Easy to use and effective.
Rating: 4.3

  • Application Area:Molecular biology

"The product is effective and yields better quality RNA."

Review date: 26 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UMD Medical School



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Extremely effective in purifying RNA.
Rating: 4.7

  • Application Area:Research

"Product is extremely effective in purifying RNA. The only recommendation that I have is for the spin columns to click in to the waste collection tubes. I have had many spin columns pop out of the waste collection tubes and it is not ideal."

Review date: 26 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Minnesota Duluth Medical School



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Quick and easy to use.
Rating: 4.7

  • Application Area:RNA extraction from wastewater

"A slight annoyance is that the filter columns do not click into the waste collection tube but otherwise quick and easy to use."

Review date: 20 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Minnesota Duluth



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fast, easy, concise.
Rating: 5.0

  • Application Area:Analyze SARS-CoV2 wastewater samples

"Great product, very fast and efficient. It is nice that the kits come with all the materials we use, including trizol and DNAse. One problem we would like to see resolved is the attachment of the Zymo spin columns to the collection tubes. This increases the risk of contamination."

Review date: 20 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: University of Minnesota



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great kit with excellent recovery.
Rating: 5.0

  • Application Area:Extraction of SARS-CoV-2 from wastewater for epidemiology

"These are easy to use and easy to store. The big kits come with Trizol and the room temperature storage for the DNase makes this kit very easy to use for a high throughput lab."

Review date: 20 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to use and high-quality RNA extraction result.
Rating: 5.0

  • Application Area:RNA extraction

"Easy to use and high-quality RNA extraction result."

Review date: 20 May 2021 | Direct-zol™ RNA Microprep


  • Status:

    Reviewer

  • Member since: 2021

  • Organization: West Virginia University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fantastic product!
Rating: 5.0

  • Application Area:RNA purification for downstream qPCR

"DirectZol by Zymo is a great product that has drastically increased the effectiveness of RNA purification of samples. It has allowed us to obtain more RNA in a shorter amount of time, and has overall streamlined the process of RNA extraction for downstream qPCR application."

Review date: 20 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: UW-Madison



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
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Good purchase for bacterial RNA extraction.
Rating: 4.0

  • Application Area:RNA extraction for transcription analysis

"I contacted their service about our organisms. They provided good ideas and the yield is good. We have been using this for couple years now. Nice and simply cut down work time for RNA extraction a lot compared to traditional Trizol protocols."

Review date: 20 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Massachusetts General Hospital



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great, high yield RNA isolation.
Rating: 5.0

  • Application Area:Isolation of RNA from cells/EVs/Virus

"We got very high quality yield RNA compared to traditional Qiagen extraction kits. Much easier than phenol/chloroform extractions from TRIzol. Highly recommend. using this product!"

Review date: 20 May 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Universidad Pablo Guardado Chávez



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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The best for the job!
Rating: 5.0

  • Application Area:RNA extraction from marine sediments

"This product was very easy to use. For RNA extraction from a marine sediment, I tested several protocols and kits and with Direct-zol RNA Microprep I obtained the best quality of RNA."

Review date: 16 Mar 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Stanford University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It is a really good product for our lab common supplies.
Rating: 5.0

  • Application Area:RNA microprep

"It is fast, easy to use and we get quality results."

Review date: 16 Mar 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Duke University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results.
Rating: 5.0

  • Application Area:Extract RNA from cells to analyze gene expression

"I manually extracted RNA from the cells and tissues, and sometimes had issues with RNA quality, especially when I extracted RNA from the cells (e.g., low A260/A230 ratio). So we decided to use the Direct-Zol RNA Microprep. The kit is easy to follow and I got enough amount of RNA for qPCR. I tried both 12-well and 24-well plate-seeded cells, and kit successes to give me enough amount of RNA with good quality."

Review date: 16 Mar 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2021

  • Organization: Icahn School of Medicine at Mount Sinai



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Fast and effective!
Rating: 5.0

  • Application Area:Extract RNA from whole blood samples

"This kit is very user friendly and simple to use. The protocol is fast, but this does not compromise the quality of the RNA that is extracted. I highly recommend this kit, particularly for high throughput extraction."

Review date: 16 Mar 2021 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: The Rockefeller University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Thrilled with this product!
Rating: 5.0

  • Application Area:Biochemistry

"Zymo Direct-Zol RNA Microprep is a game changer in our workflow. The ease of use, amazing yield and purity of RNA is unmatched. It has significantly increased our workflow and productivity. The samples are reproducible and reliable."

Review date: 04 Dec 2020 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: UC Berkeley



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product, highly recommend.
Rating: 5.0

  • Application Area:Extract RNA from bacteria

"This is an excellent product for extracting high quality RNA quickly and easily. I have used RNA extracted with this kit for RNA-Seq and I got great data."

Review date: 04 Dec 2020 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Southern California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results!
Rating: 5.0

  • Application Area:RNA extraction of invertebrate samples

"Achieve high-quality results using this! I have tried different kits and this one gives me the best results. It is easy to use and the whole process is pretty quick!"

Review date: 06 Mar 2020 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: The George Washington University



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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So much easier than traditional Trizol extractions - still great results!
Rating: 4.7

  • Application Area:RNA extraction

"I have been using Direct-Zol for more than a year now and it is a great alternative to otherwise difficult phenol-chloroform extractions. Instead of labor-intensive and skilled phase separation, the entire sample can be isolated on a column and carried out as a regular extraction. This kit gives high yield, high quality, and reproducible results in a much more efficient way than traditional Trizol extractions, but still allows the user to preserve samples in Trizol."

Review date: 16 Dec 2019 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Southern California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Convenient, fast, reliable
Rating: 5.0

  • Application Area:Extracting high-quality RNA for library prep

"I was the first one to try a single individual (~1 mm) RNA-seq in the lab and the RNA quantity and quality are critical to the success of my experiment. I searched online for a while to look for an RNA extraction kit and I felt Directzol microprep looks like a good fit, so I gave it a try. It is convenient and fast, and most importantly, it gave me success for my first single individual RNA-seq! Still use it now!"

Review date: 11 Dec 2019 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: WSU



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Extremely versatile, easy to use, and highly reproducible kit!
Rating: 5.0

  • Application Area:Tick immunology

"This kit saves so much time in comparison to their competitors - I'm able to process up to 24 samples in 1-1.5 hours. With the experiments I commonly undertake (usually up to 100 samples/ea), that is a HUGE time saver. And the price can't be beat, especially given how simple the isolation procedure is and the great reproducibility of the results. We are a multi-faceted lab that uses this kit to not only isolate RNA from human cell lines, but also from tick and fruit fly cell lines and whole or dissected tick tissues. Very versatile! I've never had an issue with the company either, which has always been an exceptional interaction!"

Review date: 27 Nov 2019 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Karolinska Institute



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Good and robust kit, competes well with the all-time favorites.
Rating: 4.7

  • Application Area:RNA extraction from low sample amount

"RNA quality is sufficiently high for downstream applications (functional assays as well as molecular biology). We changed protocol a little and use only the H2O-phase after phenol-chloroform separation for isolation. Also we added a required addition of the DNAse digestion step to the protocol. Our RNA is almost completely DNA free."

Review date: 27 Nov 2019 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Miami



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Very easy to use and user friendly
Rating: 5.0

  • Application Area:RNA extraction

"I found it very easy to use. User friendly, outstanding results. Got a grant using results from this micro RNA kit. Got a promotion."

Review date: 10 Nov 2019 | Direct-zol™ RNA Microprep
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Leeds



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Excellent RNA yield for qPCR experiments!
Rating: 5.0

  • Application Area:RNA extraction and purification from brain and spinal cord tissue

"This product is extremely effective for obtaining high quality RNA from tissue. We used brain and spinal cord for obtaining RNA for qPCR experiments and the results were excellently. The kit was easy to use and instructions were clear and provided alternatives should we need to change the protocol to fit our needs. Zymo Research is quick to respond to needs and orders. The price of the kit was well worth it as the RNA was of high quality and we could extract and purify it with ease thanks to the kit."

Review date: 05 Jun 2019 | Direct-zol™ RNA Microprep
The Direct-zol™ RNA Kits provide a streamlined method for the purification of up to 100 µg (per prep) of high-quality RNA directly from samples in TRI Reagent® or similar. Total RNA, including small RNAs (17-200 nt), is effectively isolated from a variety of sample sources (cells, tissues, serum, plasma, blood, biological liquids, etc.).

Product Overview

Direct-zol™ RNA Microprep by Zymo Research product image

Direct-zol™ RNA Microprep

Manufacturer Zymo Research  |  Available Worldwide

4.9 / 5.0 | 26 reviews