CyTOF® XT
The next-generation mass cytometer, CyTOF XT™, redefines high-parameter cytometry with advances in automation, throughput, time to results and total cost of ownership. Built to simplify the design and execution of deep cell profiling studies, CyTOF XT standardizes sample analysis with reproducible workflows and automation to accelerate novel therapeutic development and improve human health.
Great technology
Analyze cellular protein expression in human samples
Mass cytometry is a great method allowing the analysis of samples without some of the hassles of standard flow cytometry, such as compensations. The price of the material and reagents can be a little expensive and limit users/usage, but the customer service and technical support is always exceptional.
Review Date: 7 Feb 2022 | Standard BioTools Inc.
Mass cytometry, with detection by TOF, has been a transformative single-cell technology in immunology, immunophenotyping, oncology and infectious disease studies for a decade. It is in use in over 150 clinical trials worldwide and is cited in more than 1,200 peer-reviewed publications.
CyTOF® XT is the next evolution of this powerful tool: the most technologically advanced and yet affordable, easy-to-use mass cytometer to date.
It delivers all the benefits of CyTOF technology while simplifying operation and automating sample acquisition, eliminating the need for specialized instrument operators.
With a reduced purchase price and lower cost of ownership and installation compared to previous mass cytometry systems, you can’t afford not to add CyTOF XT™ to your toolbox.
XTra Clarity
The precision of measuring marker expression using CyTOF XT is unmatched by fluorescence cytometry methods. Cleaner signals generate more accurate data.
- Minimal or no background signal is seen in detection channels
- No signal compensation or deconvolution is required after data collection
- Panels of 40 or more markers are common. Over 100 examples are peer-reviewed and published
- CyTOF XT enables a very broad range of high-parameter cytometry applications
XTra Autonomy
CyTOF XT automation expands what your lab can accomplish by simplifying daily workflows and freeing operator time for other tasks.
Chilled sample carousel
- Cools to 4–8 °C
- Holds twelve 5 mL and one 15 mL sample tube
Walk-away sample acquisition
- Acquire up to 13 different samples and panels in a single batch run
- Sample pellets are automatically resuspended with addition of normalization beads
Automated clog sensing
- Software and hardware innovations provide internal fluidics monitoring of clog formation
- An unclogging routine is automatically activated by the fluidics system
XTra Efficiency
Simplified front-end assembly, a bottle tray for solutions and automated tuning minimize maintenance and calibration.
Easy daily setup
- High-capacity solution reservoirs need attention only once a week
- Daily instrument cleaning takes just minutes
Automated system tuning
- Only a single daily optimization with EQ™ Calibration Beads is required
- No additional system adjustments or optimization is needed for any panel or sample type
Real-time signal optimization
- Detector voltage adjusts automatically to maintain optimal signal detection during extended acquisitions
For Research Use Only. Not for use in diagnostic procedures
Brochures
CyTOF XT: The next evolution
Powered by mass spectrometry and CyTOF technology, mass cytometry elevates cell analysis with a level of speed, precision and reproducibility not enabled by other single-cell platforms.
CyTOF XT further enhances the capabilities of mass cytometry with workflow automation that simplifies sample processing and data acquisition. Download the brochure to find out more.
Applying CyTOF solutions to cancer immunotherapy clinical trials
It is critical for immunotherapy clinical trials to have an in-depth picture of the immune response to disease and to therapeutic treatments to better identify predictive markers, biomarker translation and understanding mechanism of action.
Explore how CyTOF™ – a single-cell proteomics platform from Standard BioTools – can capture relevant immune metrics and highly multiplexed surface and functional markers simultaneously, to uncover unique biomarkers.
CyTOF XT: The next generation of mass cytometry
Learn more about key CyTOF XT features including fully automated acquisition with clog sensing and new data processing, making CyTOF XT the most affordable and flexible high parameter cytometer.
The new CyTOF XT: Reimagine cytometry
Powered by mass spectrometry and CyTOF technology, the CyTOF XT further enhances the capabilities of mass cytometry with workflow automation that simplifies sample processing and data acquisition.
CyTOF XT: The next evolution of flow cytometry
Simplify your high-parameter cytometry and accelerate your single-cell profiling studies with the new CyTOF XT flow cytometer from Fluidigm.
CyTOF XT redefines cytometry with advances in automation
A new platform to simplify deep profiling of the human immune system
























