Cyto-Mine® by Sphere Fluidics Ltd.
Status:
Reviewer
Member since: 2019
Organization: Fujifilm diosynth biotechnologies
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- Ease of use
- After sales service
- Value for money
Excellent instrument, using innovative technology.
Application Area: Cell line development
"We have integrated the Cyto-Mine into our cell line development workflow which has allowed us to shorten our timeline without compromising on the quality of the cell lines that we generate. We have found the instrument to be very user friendly. The support offered by Sphere Fluidics has been excellent and we are very happy with the purchase. The ability to image the picodroplets prior to dispensing into a 96-well plate together with a 'heat-map' of the 96-well plate is a feature that we find very useful."
Review date: 06 Sep 2019 | Cyto-Mine®
Sphere Fluidics’ Cyto-Mine® is a fully integrated platform for high-throughput single cell analysis based on microfluidic picodroplet technology. By encapsulating single cells in picolitre volume droplets, Cyto-Mine® enables the rapid analysis, selective screening, sorting, imaging and dispensing of single cells into individual wells of microtiter plates. A key enabling component of Cyto-Mine® is its ability to analyze and measure secreted proteins or other biomolecules while maintaining high cell viability.
The unique workflow of Cyto-Mine® offers a solution to resource-intensive, time-consuming and expensive workflows that require multiple items of equipment by streamlining cell isolation, titer determination and assurance of a single cell progenitor while reducing timelines and costs for biologics discovery and development.
Key Features:
- Encapsulate up to 200,000 single cells or up to 40 million cells in mini-pools in one experimental run
- Assay secreted proteins or biomolecules e.g. assess cell line productivity or find rare cells in large heterogenous populations
- Selectively identify and sort ‘hit’ cells
- Image each individual cell for assurance of monoclonality to meet regulatory requirements
- Dispense individual cells directly in to 96- or 384-well microtiter plates
Product Overview
