Cultrex Reduced Growth Factor Basement Membrane Extract, Type 2, Pathclear by Bio-Techne

Manufacturer Bio-Techne  |   Model: 3533-001-02, 3533-00
For robust organoid cultures - Reduced Growth Factor Basement Membrane Extract


Cultrex Reduced Growth Factor Basement Membrane Extract, Type 2, Pathclear by Bio-Techne product image
Cultrex Reduced Growth Factor Basement Membrane Extract, Type 2, Pathclear
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Key benefits

  • Qualified for use in organoid cell culture
  • Commonly used robust and established organoid systems
  • Reduced growth factor formulation provides a more defined culture system
  • Quality controlled for performance consistency

Why use Cultrex RGF BME, Type 2?

Cultrex Reduced Growth Factor Basement Membrane Extract (RGF BME), Type 2 is a soluble form of basement membrane purified from Engelbreth-Holm-Swarm (EHS) tumor. This extract provides a natural extracellular matrix hydrogel that polymerizes at 37°C to form a reconstituted basement membrane. Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma and that play an essential role in tissue organization by influencing cell adhesion, migration, proliferation, and differentiation. The major components of BME include laminin, collagen IV, entactin, and heparan sulfate proteoglycans.

Cultrex RGF BME, Type 2 provides a proprietary formulation that is high in tensile strength and is designed for use in robust tissue organoid culture as well as other applications requiring an extracellular matrix scaffold.

Protocols utilizing Cultrex RGF BME, Type 2 for organoid cell culture

Cultrex RGF BME, Type 2 is ideal for use as a scaffold for organoid and 3D cell culture. Listed below are protocols designed by our research and development groups for organoid culture featuring Cultrex RGF BME, Type 2 as well as growth factors, media supplements, and small molecules from Bio-Techne.

Product Overview

Cultrex Reduced Growth Factor Basement Membrane Extract, Type 2, Pathclear by Bio-Techne product image

Cultrex Reduced Growth Factor Basement Membrane Extract, Type 2, Pathclear

Manufacturer Bio-Techne

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