CRISPR-Cas9 Custom Services
GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…
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GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation.
Service Details:
- Validation Services
- Donor clone services
- Stable cell line services
- Transgenic mouse services
Advantages:
- Fast delivery of CRISPR-Cas9 plasmids or mRNA transcripts
- Fully sequence-verified and transfection-ready
- Functional validations available
- Knockin donor plasmid also available
- Stable cell line or transgenic mouse services available
CRISPR-Cas9 Specificity: Taming Off-Target Mutagenesis
This application note considers the mechanism of CRISPR-Cas in its application for genome editing and how it affects specificity, reports in the literature discussing CRISPR’s potential for off‐target mutagenesis, and approaches for increasing the target specificity of CRISPR-Cas.
