CombiFlash EZ Prep System by Teledyne ISCO

Manufacturer Teledyne ISCO  |  Available Worldwide
4.8
/
5.0
  |  26 reviews

The CombiFlash EZ Prep offers streamlined Flash and Prep HPLC chromatography in one compact, easy-to-operate unit. With just two clicks, users can switch from pre-purifying samples on Flash to generating submission-quality compounds on Prep HPLC. Teledyne ISCO's RFID-encoded collection racks ensure proper loading every time and allows users to hot-swap racks during separation for virtually limitless fraction collection capability.  


CombiFlash EZ Prep System by Teledyne ISCO product image
CombiFlash EZ Prep System
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Average Rating: 4.8
26 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2018

  • Organization: Lodo Therapeutics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Must have for any natural product labs.
Rating: 5.0

  • Application Area: Natural products

"It is one of the best chromatography technology upgrades from the open column days! Though it will not replace the traditional one, the function is very similar and extremely easy to use compared to HTS and are made even faster with the advent of combi flash systems."

Review date: 16 Jul 2021 | CombiFlash EZ Prep System
  • Status:

    Expert Reviewer

  • Member since: 2010

  • Organization: Dr D Y Patil Institute of Pharmaceutical Sciences And Research



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Best flexible equipment
Rating: 4.7

  • Application Area:Analytical and Bioanalytical

"This system comes with dual function purification which enables to use flash and prep system at the same instrument. It provide great flexibility without compromising the performance. This system is also compatible with Automation Modules for great performance."

Review date: 18 Mar 2021 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: GNF-Novartis



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Very easy to use and collect fractions.
Rating: 4.3

  • Application Area:Analytical chemistry

"Very easy to use and our chemists don't have too many problems with the instrument, unlike some of our other HPLC prep systems."

Review date: 11 Dec 2020 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Croda



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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A must-have in the natural products lab.
Rating: 5.0

  • Application Area:Purification of natural products

"The Teledyne CombiFlash system is the workhorse in our lab for fractionation and purification of natural products. Using RediSep Gold C18 and silica cartridges, we routinely to purify natural products from complex extracts on this system without having to resort to more lengthy HPLC methods. This automated system is much better than running benchtop columns!"

Review date: 11 Dec 2020 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2015

  • Organization: IFF



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Super easy to use and resealable to excellent separation.
Rating: 5.0

  • Application Area:Purification of synthetic chemicals

"It is easy to use and cheaper than the competition. Service after purchase is also good and they provide matriculate care whenever the equipment has issues. Consumables such as columns are provided at discounted price."

Review date: 06 Mar 2020 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2020

  • Organization: Ono pharmaceutical



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Without this instrument MedChem would never finish their work.
Rating: 5.0

  • Application Area:Organic synthesis & small molecule compound purification

"The interface is really user-friendly and without checking the instructions, everyone understood how to use it. After the purchase of the instrument, we never refused the purification of compound. The separation is awesome!"

Review date: 28 Jan 2020 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Seton Hall University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Highly recommend their products.
Rating: 5.0

  • Application Area:Separation of phthalonitrile derivatives

"The equipment is easy to use, has a user-friendly interface and gives very good results in the separations."

Review date: 13 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Emporia State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great for repeat separations!
Rating: 4.7

  • Application Area:Purify reaction mixtures

"My postdoctoral lab had a CombiFlash EZ Prep System that hadn't been used for a couple of years and no one in the lab at the time knew how to use it. The Teledyne rep was incredibly helpful. She visited a couple of times to make sure the system was working and to show me how to use it. Anytime I had a question, she responded quickly and was very helpful. The system is very easy to use and has many great options in that you can change many parameters to get the right gradient for your separation. Some trial and error is needed to figure out the best gradient to achieve good separation. For this reason, the system is great if you are purifying the same mixture over and over again. However, if you have several different mixtures, a lot of time may need to be invested to figure out how to separate them all. In my experience, a regular column is easier and less time consuming in this situation."

Review date: 10 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Pharmatory



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Very good product.
Rating: 4.3

  • Application Area:Purification of organic compounds

"The user interface of the system is easy to use and the selection between flash chromatography and preparative HPLC is simple and clear. The only negative comment is from the injection of sample on the preparative HPLC side: The sample tends to leak out if syringe is not left on the injection port before the is started. Monitoring of the eluent levels works well and the purifications are successful."

Review date: 10 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Neogen



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Very good instrument and easy to operate.
Rating: 4.7

  • Application Area:Chemical compounds separation

"The equipment really helped me to make the purification process go faster than usual. The price was fair if you consider the outcome. If used as an automated step for purification of chemical compounds it has good benefits."

Review date: 08 Jun 2019 | CombiFlash EZ Prep System


  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Millersville University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It's our go to instrument!
Rating: 5.0

  • Application Area:Analysis and separation of organic reactions

"I wish I had one of these 40 years ago. It would have made graduate school research a lot easier."

Review date: 08 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Greenwich



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great instrument, something we can no longer work without.
Rating: 5.0

  • Application Area:Medicinal chemistry

"The CombiFlash is used in our lab for purification of our medicinal chemistry. It is easy to use and there are a variety of tools and options."

Review date: 08 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Evonetix



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Wonderful machine, so glad that we have it.
Rating: 5.0

  • Application Area:Small molecules purification

"Easy to use, love the automation of the system, it helps to save lots of time."

Review date: 08 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Florida



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Can’t imagine going back to traditional coloums.
Rating: 5.0

  • Application Area:Purification of crude of chemical reactions and plant extracts

"Easy to use, you can save the method to reuse the same gradient. Produces reproducible results compared to traditional coloums. CombiFlash save time, solvents, and money. Also, you can collect only the peaks you want and discard the others."

Review date: 08 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Lumen Agilis



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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A wonderful solution that's made our life easier by being so simple and easy to use.
Rating: 4.0

  • Application Area:Product purification

"We do achieve high quality and reproducible results. Its easy to use. The purchasing process was easy and they were helpful in identifying the model type and consumables that I would need."

Review date: 08 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Dayton



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great, can't imagine work without it.
Rating: 5.0

  • Application Area:Synthetic organic chemistry

"This is a great product. I have purchased this to make column chromatography easier for my undergraduate students and it exceeded my expectations. Highly recommend the yearly service, especially if you have a lot of students using it. Great service staff and customer care."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Baylor University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great product, saves a lot of time and labor.
Rating: 4.7

  • Application Area:Organic chemistry, synthesis and catalysis, drug discovery

"It's very user friendly but also very smart. Everyone in the lab knows how to use it after brief training. It saves a lot of solvents and labor especially on large scale work. You can trace the signals with the equipped UV detector and/or ELSD detector. The ELSD detector is especially useful for compounds that are not UV active."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: GSK



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Really easy to run and maintain.
Rating: 4.7

  • Application Area:Compound purification

"I find the machine really easy to run and train on. Compared to other manufacturers' models that are more expensive, our machine is great. I will definitely recommend this machine when we expand the group."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Verseon Corporation



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great equipment, can't live without it.
Rating: 5.0

  • Application Area:Purification of small molecules

"The machine is very reliable and easy to use. It's one of the routine machines I would like to use every day. Using it is carefree and there's almost noting to worry about. The separation capability is very good and in most cases if I can see separation on TLC the machine can purify it."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: The Oho State University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great instrument and good value money.
Rating: 5.0

  • Application Area:Purification of drug-like molecules

"This is one of the best instruments every organic chemistry laboratory should have. It saves time (usual purification finishes in 15 minutes), solvents (compared to manual column purification), and labor. The reproducibility of purification is awesome. Columns and cartridges are little expensive but its worth spending money on it."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Samumed LLC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great products.
Rating: 5.0

  • Application Area:Sample purification

"New ISCO's are very good. I use the Gold columns the most."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: UTSW



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    4 out of 5
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Great customer service.
Rating: 4.7

  • Application Area:Chemistry synthetic lab

"It's very easy to use. Ocasionally it has some software bugs. Customer service is a very essential part of this product."

Review date: 07 Jun 2019 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: UNC-CH



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Recommended instrument.
Rating: 4.7

  • Application Area:Chemical purification

"I have always preferred ISCO products for my compound/intermediate purification needs and this instrument does not disappoint."

Review date: 25 Oct 2018 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2010

  • Organization: Vertex Pharmaceuticals Canada



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Great machine, small footprint
Rating: 4.7

  • Application Area:research purification

"Extremely simple to use, same interface has other isco system. Efficient, good purification capacity. Good loading capacity. Users are Happy"

Review date: 05 Dec 2016 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Ppg Industries, Inc.



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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One of the most useful instrument in a synthesis lab.
Rating: 4.7

  • Application Area:Purification

"This instrument frees researcher's hands so they can focus on more important task."

Review date: 30 Mar 2016 | CombiFlash EZ Prep System
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Xavier University Of La



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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It is the most useful instrument in my research lab.
Rating: 5.0

  • Application Area:Purification of synthetic reaction mixtures

"This instrument is very easy to use. My undergrad students use it routinely. We get good quality purification of compounds. I would certainly recommend it to others. In fact, this system has been purchased by other faculty in the Chemistry department once they saw how useful and easy to handle this instrument is. My columns are now completed within an hour."

Review date: 30 Mar 2016 | CombiFlash EZ Prep System
Streamline Flash and Preparative HPLC chromatography with a compact, easy-to-operate unit The CombiFlash EZ Prep streamlines the purification process, quickly switching from Flash to high-pressure preparative chromatography in just two clicks. Pre-purify on Flash followed by Prep for submission quality compounds. 
 
User-friendly PeakTrak® software controls both Flash and Prep HPLC chromatographic conditions. Additionally, PeakTrak integrates all detector options, including the CombiFlash PurIon mass spectrometer for single point control.
 
Features:
• Up to 3500 psi (240 bar) and 200 mL/min 
• Run Prep HPLC columns up to 50 mm in diameter (including 5 µm particle diameter) 
• Flash purification for 10 milligrams to 33 grams followed by final compound purification on high performance columns 
• UV, UV-Vis, ELSD and MS detection options available
• Switch between normal and reverse phase solvents

Product Overview

CombiFlash EZ Prep System by Teledyne ISCO product image

CombiFlash EZ Prep System

Manufacturer Teledyne ISCO  |  Available Worldwide

4.8 / 5.0 | 26 reviews