RediSep ® Gold ® C18
Purify medium to high-polarity compounds – without HPLC cost or complexity

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Great MPLC column
Separation of complex mixture
Nice separation of desired product from complex mixture of compounds.
Review Date: 28 Mar 2022 | Teledyne Labs
Great separation for compounds that would be hard to purify by other methods.
Chromatography
Great separation for compounds that would be hard to purify by other methods, easy to use and set up. Being able to use normal or reverse phase is a great benefit. After sales team always available for any queries on how to use/set up etc.
Review Date: 10 Jun 2019 | Teledyne Labs
RediSep Rf Gold Cyano high performance columns have a cyano bound silica gel that has an intermediate polarity, between that of normal and reversed phase silica gel. This makes them a versatile tool for separation.
RediSep Rf Gold Cyano columns, when used in normal phase conditions, will perform comparably to RediSep Rf Gold normal phase silica gel using similar solvents. In reversed phase conditions, performance is similar to RediSep Rf Gold C18 Reversed-phase columns, although the elution order of compounds may be different. In summary, RediSep Rf Gold Cyano columns are a useful alternative purification media.
RediSep® Rf Gold® Cyano Features:
- High flow rates for fast resolution of target compounds.
- Column sizes available for purifying milligrams to several grams.
- RFID technology for automatic set up on compatible instruments.
- Fits all Isco CombiFlash automated organic purification instruments.
- Long shelf life in airtight, resealable packages.
- Luer lock end fittings.
Save Time and Money by Purifying Peptides Yourself
This application demonstrates how the CombiFlash® EZ Prep system with PurIon Model L mass spectrometer and RediSep® Prep columns allow research labs to save time and money by purifying crude peptides received from outside synthesis labs themselves. By purifying peptides as needed, a continuous supply of fresh peptide is always available as peptides can degrade over time during storage.
Purification of Delicate Compounds with RediSep Rf Gold® Diol and Cyano Columns
Many compounds are difficult to purify because they decompose on the column. This application note demonstrates the synthesis and purification of an epoxide compound with a RediSep Rf Gold Diol and RediSep Rf Gold Cyano column. The epoxide makes an excellent model for other unstable compounds as epoxides commonly decompose on silica gel. Unstable compounds are often purified using a series of liquid-liquid extractions. Purifying such compounds on a column where the amount of solvent used and evaporation is reduced is desirable.
Strategies to Purify Carbohydrate Based Compounds with Flash Chromatography
Carbohydrate compounds are synthesized for a variety of purposes; they are used as probes in life sciences such as mechanism studies. This application note provides a summary of methods for purifying compounds containing carbohydrate moieties and detection/fractionation of these compounds. Synthesized compounds and natural products are examined with examples from the published literature using CombiFlash® systems or RediSep® columns from Teledyne Isco.
Purification of Cannabimimetics and Cannabinoids for Standard Reference Materials and Forensic Analysis via Flash Chromatography
The market for synthetic cannabinoids has grown since 2008 beginning when the “spice herbal mixture” was introduced. Although the original “spice” compounds have been outlawed in many countries, renegade chemists have produced new cannabimimetic compounds that are not illegal. This application note describes how Telendyne’s Isco Combi-Flash systems and RediSep Rf Gold columns can be used to purify these new compounds for structural characterization in a forensic setting.
Wide Polarity Range Flash Purifications
Natural sources contain a large number of compounds that range from very non-polar materials, such as terpenes, to highly polar compounds such as tannins. Wide Polarity Range Chromatography is a method to resolve complex mixtures into various groups of molecules that are easier to purify in subsequent steps. This poster describes columns suitable for use with Wide Polarity Range Chromatography including the RediSep Gold® C18, diol, and silica and the RediSep® alumina columns.















