Collagen Type I, Rat Tail by ibidi GmbH

• Provides in vivo-like extracellular matrix (ECM) structures
• Non-pepsinized, native collagen for modelling biological ECM in gel matrices
• Fast polymerization facilitates optimal cell distribution in 3D gels

Applications:

• 3D cell culture in in vivo-like matrices
• Live cell imaging in a 3D environment
• Creating a 3D scaffold for organoids and spheroids
• Chemotaxis assays in 3D collagen gels using the µ-Slide Chemotaxis
• Cell migration assays of suspension cells (e.g., leukocytes)
• Coating of cell culture vessels with a thin collagen layer to promote cell attachment
• Cell differentiation studies in a 2D versus 3D environment
• Highly suited for fluorescence microscopy due to low autofluorescence

Technical Features:

• High-quality purified protein from rat tendons
• Highly standardized manufacturing process with stringent quality control
• Mild manufacturing process for highest levels of nativity
• Detailed protocol provided for easy handling
• Shipping on cool packs and storage at –20°C for well-defined quality and reproducibility
• Available in 2 concentrations: 5 mg/ml for standard applications and a high-concentrated solution with 10 mg/ml for special applications
• Highest level of natural cross-linking on the market (highest quality grade)
• High viscosity: special pipettes for highly viscous solutions are recommended
• Low autofluorescence