BIOne Single-Use Bioreactor System by Distek, Inc.

Manufacturer Distek, Inc.  |  Available Worldwide
The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.   


BIOne Single-Use Bioreactor System by Distek, Inc. product image
BIOne Single-Use Bioreactor System
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The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds. Upon media addition, the liner expands and molds to the glass vessel, preserving the geometry of the existing bioreactor. 

The BIOne SUB’s liner material emulates the large-scale SUBs used in pilot and commercial biopharma production facilities around the world. Performing R & D studies using the most similar material on the market streamlines your tech transfer and can de-risk your process BEFORE transferring to pilot scale.

CUSTOMIZABLE ABOVE & BELOW THE HEADPLATE

  • 2L & 5L Working Volume
  • Optional Single-Use pH Probe
  • Increased Throughput
  • Weldable Tubing
  • Flute, Micro & Open Pipe Sparging Options
  • Non-Invasive DO & Optional pH Probe Ports
  • USP Class VI Materials
  • Repligen® ATF Perfusion Tube Compatible
  • Animal Derivative-Free
  • Low Antioxidant Liner Material
  • Compatible with Most Manufacturers’ Glass Vessels and Controllers

DO & pH PROBE PORTS

  • Non-Invasive (Amperometric DO/Optical pH)
  • PG-13.5 (Optical DO/Electrochemical pH)
  • Optional Integrated Single-Use pH Probe

PITCHED BLADE IMPELLER

  • Single or Dual Impeller

SPARGING OPTIONS

  • Flute Sparger (7 x 1.5 mm hole)
  • Micro Sparger (20-40 μm pore size)
  • Open Pipe Sparger (1 x 3.0 mm)

LOW ANTIOXIDANT LINER MATERIAL

  • Outer Layer (LDPE) – Mechanical Strength
  • Middle Barrier Layer (EVOH) – Gas Barrier
  • Contact Layer (ULDPE) – Cell Culture Compatible, Biologically Inert
     

Product Overview

BIOne Single-Use Bioreactor System by Distek, Inc. product image

BIOne Single-Use Bioreactor System

Manufacturer Distek, Inc.  |  Available Worldwide

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