7010B Triple Quadrupole GC/MS

In this application note, find out how experts design robust analytical methods to investigate the potential contaminants and routes of contamination in our drinking water.

The full video is available to watch on The Scientists’ Channel®.

In this application note, Agilent Technologies describes how the Agilent MassHunter Optimizer software for GC Triple Quad (GC/TQ) can help generate multiple reaction monitoring (MRM) transitions for newly added compounds using an Agilent 8890 GC coupled to an Agilent 7000D GC/TQ system.

The Agilent 7000D triple quadrupole GC/MS is the latest model of the most successful GC/TQ in history. The right choice for most applications, the 7000D is the fourth-generation version of the GC/TQ used by agencies around the world to create and validate many now-standard GC/MS/MS methods.

Download this compendium of application notes, featuring analyses performed using triple quadrupole GC/MS/MS.

Twenty-seven GC-amenable pesticides and their isomers regulated in the cannabis industry in North America stand out as challenging to analyze using liquid chromatography-triple quadrupole mass spectrometry (TQ LC/MS) with electrospray ionization (ESI). In this application note, Agilent Technologies outlines a complete workflow that achieves required limits of detection (LOD), limits of quantitation (LOQ), accuracy, and precision defined by the California Bureau of Cannabis Control (BCC) and Health Canada in dry cannabis flower.

In this application note, Agilent presents a multiresidue method for the analysis of PAH residues in salmon and beef. This workflow, consisting of liquid extraction, Captiva EMR–Lipid cleanup, and analysis by GC/MS/MS, promises high matrix cleanup, excellent analyte recovery, and precise results for multiresidue analysis of PAHs.

In this application note, Agilent utilizes the 8890/7000D and 8890/7010B triple quadrupole GC/MS systems for the quantitation of GC-amenable incurred pesticides in strawberries. These systems are shown to be suitable for the determination of pesticides in strawberries at the tolerances established by the US EPA, ranging from 10 to 25,000 ppb.

In this application note, Agilent describes an analytical method for determining multiresidue pesticides in salmon. The sample preparation method is based on liquid extraction followed by Agilent Captiva EMR—Lipid cleanup and analysis with Agilent Intuvo 9000 GC and 7010B Triple Quadrupole mass spectrometry (GC/MS/MS).

This application note investigatesd pumpkin seed oil, which has a fatty and complex matrix with a high probability for PAH contamination. The fatty acid compositions in pumpkin seed oil include mainly palmitic acid, stearic acid, oleic acid, and linoleic acid. Pumpkin seed oil is produced by toasting pumpkin seeds above 100 °C, and pressing the seeds, using a hydraulic press, into a dark green oil. In addition to the roasting process, the other possibility for PAH contamination in pumpkin seed oil is that there is no refining step, which can drastically decrease the amount of PAHs.

Today’s high throughput food laboratories require reliable and timely pesticide residue analysis of varied food samples. To gain the highest productivity of the analytical instrumentation, the JetClean Self-Cleaning Ion Source was successfully applied to pesticide residue analysis, significantly reducing the need for manual source cleaning and increasing the sample throughput of the GC/MS system. Similarly, applying the StreamSelect (SS) configuration to LC/MS systems eliminates the idle time of the MS, and increases the LC/MS system throughput. Both the JetClean and the StreamSelect operations are executed automatically using MassHunter SW.

The need for fast screening of samples is desired across many fields of study, from crime laboratories analysis of seized drugs, to verify RoHS compliance of plastic commodities. Conventional screening with GC-MS requires sample preparation of dissolution, dilution and/or headspace sampling and long GC analysis times. Typical application of direct insertion real-time MS provides a quick analysis of various sample types but does not have chromatographic separation of the analytes, causing increased time of human review. Direct insertion GC-MS is an easy-to-use screening technique, and offers fast analysis with GC separation and mass spectral confirmation in under a minute.

This video introduces the Jet-Clean Self-Cleaning Ion Source, a technology that allows operation for months without having to clean the source. This is designed to improve sensitivity, improve peak-shape, and prevent continuous recalibration.

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