XploRA - Raman microscopy

The development of Raman spectroscopy has come a long way since its discovery in 1928. Its combination with optical microscopy in the latest, next-generation confocal Raman microscopes has enabled fast, non-destructive, non-invasive hyperspectral imaging of samples without the need for sample preparation in most cases.

In this application compendium, we look at some of the wide-ranging applications of Raman microscopy to address various formulation challenges encountered by the pharmaceutical and cosmetics industries. In particular, we consider HORIBA Scientific’s latest confocal Raman imaging microscope, the LabRAM Soleil™, designed to make Raman imaging faster and easier than ever before.

Download the free eBook to discover how Raman microscopy can yield information on molecular structures, crystal phases, polymorphisms and much more, as we cover:

• Characterization of pharmaceuticals, including compound distribution, chemical homogeneity and more
• Characterization of cosmetics for perfect formulations
• Raman spectroscopy as an essential tool in pharma

In connection with investigation of fraud, counterfeiting, blackmail and anonymous letter cases, forensic experts frequently have to find out whether a document was altered after signing. In these cases the sequence of crossing printer and pen ink line often needs to be determined in order to resolve whether any of the printed text was printed after the signature. When there are no intersecting lines between the printed text and the pen ink lines, standard techniques used for sequencing are not applicable. This note demonstrates the application of micro-Raman spectroscopy to investigate the chronological sequence of printed and hand-written features on the documents even if there are no intersecting lines.

The knowledge of the chemical composition of aerosols is of great importance due to their potential adverse effects on the environment and human health. Due to the small size of typical aerosol particles, the challenge is physicochemical characterization of aerosols at the micron scale. This application note explores the use of confocal Raman microspectrometry for the characterization of aerosol particles and other applications.

Read this application note to learn about the ability of Raman spectroscopy to distinguish the number of graphene layers and any defects present. Also learn about the exciting advantages to using graphene as a substrate in Raman spectroscopy.

Watch this video to learn how the XploRA™ from Horiba brings chemical identification directly to your microscope. The XploRA can be coupled to both upright and inverted microscopes, allowing analysis of all sample types, ranging from semiconductors and nano-materials, through to biological cells and tissues.

For the correlative analysis of Raman, AFM, AFM-Raman, cathodoluminescence and fluorescence data and microscopy images

Learn how to obtain accurate, non-destructive, information on polymers in this on-demand webinar

Affordable Raman engine aims to provide OEM customers with unmatched detection limit

The agreement will allow materials science researchers to benefit from solutions combining HORIBA’s advances in AFM instrumentation with Qnami’s innovation in quantum sensing

Join us on Monday, September 28, for this expert-led webinar on the intricacies of Raman technology

More powerful nanoparticle analysis with Raman spectroscopy, hyperspectral imaging and enhanced darkfield illumination on the same microscope platform

CLUE Series offers scalable platform for imaging and spectroscopic analysis of nano-objects with SEM and dual SEM/FIB (Focused Ion Beam) microscopes.