VIA Freeze™ controlled rate freezers
The VIA Freeze range of controlled-rate freezers are liquid nitrogen-free. They combine customizable freezing profiles, electronic control systems, and a conduction cooling method to optimize GMP-compliant cryopreservation.
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Use the VIA Freeze Uno unit as a portable instrument or in a laboratory setting. Select VIA Freeze Duo for proof of concept experiments or low-volume production. Choose VIA Freeze Quad unit for production settings in a laboratory environment.
- Controlled cooling. Maintain cell function and viability with therapy-specific freeze profiles and precise temperature control.
- Consistent quality. Remove heat evenly from all samples thanks to conduction cooling. Standardize by reliably delivering profiles between networked units.
- Clean room compatibility. Streamline manufacturing processes. Eliminate risks and infrastructure costs associated with liquid nitrogen.
- Supports cGMP-compliant cryopreservation. Ready to integrate with cGMP process validation procedures. Controls designed to meet 21 CFR Part 11 regulations.
- Versatility. Increase productivity without changing processes between VIA Freeze models. Options for 24–192 cryogenic vials, cryobags up to 250 mL, and straws.
- Manufacturing automation. Incorporate freezing processes and profile run data into a complete digital batch record within Chronicle software. Monitor processes.
AAV manufacturing workflow
In this application note, Cytiva provides information on the objectives, considerations, and strategies for each step of an adeno-associated virus (AAV) manufacturing workflow. AAV is a crucial tool in genetic research and gene therapy. It efficiently delivers genetic material into target cells, aiding in the study of gene function and offering potential treatments for genetic diseases. Its nonpathogenic nature and tissue-specific variants make it a promising candidate for advancing medical therapies and improving patient outcomes.
