Thermo Scientific™ Nicolet™ iS50 FTIR Spectrometer
Solve analytical challenges with ease using the Thermo Scientific Nicolet iS50 FTIR Spectrometer, featuring purpose-built accessories and integrated software - making it an all-in-one materials analysis workstation.
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I made three publications using the instrument. I is great for research work.
Detecting silver nanoparticles prepared using essential oils
At the beginning, the results were very good with high resolution. The there were too much noisy in the sample spectra. It is not easy to understand the software or make changes in the settings. I talked to the person on charge who installed the instrument, then someone else came and tried to fix but the problem was not solved. Another try was to solve the problem online using software to make my lab visible, but I refused.
Review Date: 24 Jul 2023 | Thermo Fisher Scientific
Great results, with ease of operation!
Analytical Methods
This instrument has such an easy program to use, that training other scientists on the platform has been a breeze. I want to commend Thermo Fisher in their excellent customer service and care taken when installing and performing Operational Qualifications. This instrument is truly state of the art, with a myriad of applications. It has been an immense help in our analytical methods for sample composition identification. Thank you so much Thermo!
Review Date: 18 Oct 2021 | Thermo Fisher Scientific
Great results, very easy to use and set up.
Used to analyze the spectra of different non metallic materials
The piece of equipment is very easy to use. Easy for beginners to get trained up to analyze samples and run several iterations of tests. High quality, highly precise repeatable results.
Review Date: 1 Oct 2021 | Thermo Fisher Scientific
Definitely recommend.
Gas Analysis
This FTIR will do everything that you need and more. It is very thorough, but the software can be a bit cumbersome for advance quantitation. It is my understanding that software upgrades are coming soon.
Review Date: 24 Sept 2021 | Thermo Fisher Scientific
Very capable instrument.
Gas analysis
This product is very effective. It has lots of functionality and we use it regularly. We wish the software was a bit better.
Review Date: 26 Jul 2021 | Thermo Fisher Scientific
Great little instrument that our labs cannot do without.
General analysis of organic compounds as a first screening tool
Very easy-to-use benchtop instrument, portable, small footprint. Excellent for teaching purposes on all levels at university, great screening tool. Appropriate software to install several libraries. Fast, reliable IR spectra.
Review Date: 16 Jul 2021 | Thermo Fisher Scientific
Convenient to use for quick material comparison and QC qualification.
Organic monomers and polymers
It is not very hard to use generally speaking. It does require regular maintenance and care more than other equipment.
Review Date: 24 Mar 2021 | Thermo Fisher Scientific
Great reproducibility.
Analysis of bacteria and nanoparticles
It is easy to use, and no need for any sample preparation for ATR-FTIR. However, it has not a library for assignments.
Review Date: 26 Apr 2020 | Thermo Fisher Scientific
Great instrument.
Infrared
Great instrument for both basic and research samples.
Review Date: 16 Mar 2020 | Thermo Fisher Scientific
Training and support were excellent.
QC
Easy to crack methods. Training and support were excellent.
Review Date: 6 Mar 2020 | Thermo Fisher Scientific
The Thermo Scientific™ Nicolet™ iS50 FTIR Spectrometer is an integrated materials analysis workstation designed to help laboratories address complex analytical challenges using multiple vibrational spectroscopy techniques within a single platform. Its flexible architecture enables users to begin with a standard FTIR configuration and expand capabilities over time with integrated ATR, Raman, near-infrared (NIR), and far-infrared analysis options. Designed for versatility and productivity, the system supports a wide range of materials characterization, identification, deformulation, and research workflows across industrial, academic, and government laboratories.
The Nicolet iS50 FTIR Spectrometer combines advanced hardware, purpose-built accessories, and integrated software to streamline analytical workflows. Features such as one-touch operation, dual-source capability, multiple detector options, high-resolution performance, and automated optical configuration allow users to perform diverse analyses without extensive instrument reconfiguration. Optional modules further extend functionality, enabling specialized applications including Raman spectroscopy, NIR analysis, GC-IR, TGA-IR, and advanced materials research.
Key features and benefits
- Flexible platform that can be expanded from FTIR to multi-spectral analysis capabilities
- Integrated support for ATR, Raman, NIR, and far-IR techniques
- One-touch operation with automated optical configuration options
- Dual-source capability with long-life IR and white-light sources
- Multiple detector options and high-resolution performance
- Built-in diamond ATR option for rapid analysis of powders, liquids, gels, and pastes
- Broad compatibility with Smart Accessories and specialized analytical modules
- Supports advanced materials characterization, deformulation, and method development workflows
- Scalable platform designed to adapt to evolving laboratory requirements
Applications
- Polymer and rubber characterization
- Pharmaceutical formulation and polymorph analysis
- Forensic and illicit substance identification
- Pigment, paint, and ink analysis
- Food, flavor, oil, and agricultural product analysis
- Battery and advanced materials research
- General materials identification and deformulation
- Academic and industrial research laboratories
Protein secondary structure elucidation using FTIR spectroscopy
Fourier-transform infrared (FTIR) spectroscopy is one of the most versatile analytical tools used across various disciplines. In this application note, Thermo Fisher Scientific utilizes the Thermo Scientific™ Nicolet™ iS10 and Nicolet iS50 FTIR Spectrometers, equipped with attenuated total reflection (ATR) FTIR and transmission FTIR for the determination of protein secondary structures. Structure calculations based on a protein database as well as spectral deconvolution are discussed.
Forensics Analysis Workstation: Nicolet iS50 FT-IR Spectrometer from Thermo Fisher Scientific
Watch this video to learn how the Thermo Scientific Nicolet iS50 FT-IR spectrometer, with its combination of technological sophistication, analytical flexibility, and ease-of-use, is the ultimate forensics analysis workstation.
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This video introduces the iD7 accessory for use with industry-leading Thermo Scientific FT-IR spectrometer systems. iD accessories enable a wide range of simple, practical, and affordable techniques to quickly and easily analyze samples.
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