Single Cell CRISPR Guide Enrichment Kit
Amplify a CRISPR guide sequence derived from a CROP-style vector alongside your standard RNA Sequencing Library.
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The Scale Bio CRISPR Guide Enrichment Kit is modified from our standard ScaleBio Single Cell RNA Sequencing Kit, with the added benefit of capturing a CRISPR guide sequence derived from a CROP-style vector. To maximize guide detection, we have included target-specific priming during reverse transcription, as well as PCR enrichment in the final step of library preparation. This kit enables the processing of up to 500,000 cells or nuclei per run with extended throughput, as well as the multiplexing of up to 96 samples.
High-throughput single cell screening for cancer research
Single cell analysis is reshaping the landscape of life science research—revealing rare cell types, exposing hidden heterogeneity, and delivering actionable insights into disease mechanisms that were once out of reach.
In this free SelectScience guide, discover how Scale Biosciences is leading the next generation of single cell innovations. Learn how cutting-edge, scalable platforms are transforming RNA sequencing, CRISPR screening, and DNA methylation studies—at a fraction of the cost and complexity.
You'll learn how to:
- Scale your single cell research
- Achieve ultra-high throughput RNA sequencing
- Profile CRISPR knockout experiments at scale
- Optimize DNA methylation analysis
- Combine single cell methylation libraries with targeted enrichment
Who is this eBook for?
- Cancer biologists exploring tumor heterogeneity
- Genomics and epigenetics researchers
- Functional genomics scientists running CRISPR or perturbation screens
- Bioinformaticians and computational biologists seeking scalable data generation
- Translational researchers working on drug discovery pipelines
- Core facility scientists building single cell workflows for broad use
- Academic labs transitioning from bulk to single cell approaches
- Pharma and biotech scientists advancing precision medicine
Resource details:
- Document type: SelectScience guide
- Page count: 30
- Read time: 45 mins
- Edition: 1st
