Products & ReviewLife Sciences

LMD6 & LMD7 Laser Microdissection Microscopes

Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes. Intuitive software combined with adjustable lasers and optics allow more precise cutting and collection of a diverse array of sample types.

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Description

Dissection Perfection

Laser Microdissection (LMD, also known as Laser Capture Microdissection or LCM) enables users to isolate specific single cells or entire areas of tissue. Powered by a unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest (ROI) from entire areas of tissue down to single cells or even subcellular structures such as chromosomes.

LMD is typically used in genomics (DNA), transcriptomics (mRNA, miRNA), proteomics, metabolomics, and even next generation sequencing (NGS). Researchers in neurology, cancer research, plant analysis, forensics or climate research rely on this method. Furthermore, LMD is a perfect tool for live cell culture (LCC), for cloning and re-cultivation, manipulation or downstream analysis.

We move the laser, not the sample. And we use gravity for collection. That is why our LMD6 and LMD7 systems provide you with perfectly cut, contamination-free, analysis-ready dissectates.

Application eBookLife Sciences

The power of spatial biology: A microscopy guide

Location is key to understanding biological mechanisms, from the inner workings of subcellular components to how cells form and interact across normal and diseased tissues.

Many application areas are seeing a growing trend toward spatial biology, which uses transcriptomics, imaging, and other approaches to put dissociated cellular information into spatial context.

In this free eBook, explore key microscopy techniques, across the spatial biology workflow, including:

  • Multiplexing
  • Laser microdissection
  • Removing the blur to observe fine details
  • Super-resolution microscopy
  • Ultra-structural context
  • AI-enabled spatial analysis

Plus, we look "under the microscope" at how these can be applied to study a wide range of spatial biology questions and gain expert insight into the imaging solutions designed to meet a variety of different research needs and priorities.



Application NoteLife Sciences

Laser Microdissection Combined with AmpliGrid/LOC Devices: High-Throughput for Efficient Screening

The AmpliGrid is a special form of LOC (Lab on a chip). This non-capillary system can serve as a collector for specimen material isolated by various laser microdissection devices. This note describes high throughput screening applications of AmpliGrid/LOC devices in combination with the Leica LMD6500/7000 system. Roles in cancer research and neuroscience are highlighted.

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