Evosep One
Clinical Proteomics must be Sensitive, Fast, and Robust, which Evosep One achieves with perfection
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Ease of use is unmatched! Truly makes proteomics more accessible.
Liquid chromatography
In the high-throughput environment of our proteomics facility, the Evosep One has become a necessity. Its standardised methods have effectively eliminated the traditional LC bottleneck, allowing us to analyse hundreds of samples weekly without the constant fear of capillary clogs or column degradation. The pre-column Evotip technology is the real game-changer; by integrating sample cleanup directly into the injection process, we have drastically reduced overhead and improved instrument uptime. Although local support for high-end MS hardware can sometimes be a challenge, the robust and simplified design of Evosep makes it remarkably resilient against the rigours of heavy daily use. It provides the chromatographic reproducibility required for deep-dive discovery, making it an indispensable pillar of our workflow.
Review Date: 8 Apr 2026 | Evosep
Great instrument to standarize proteomics.
Liquid chromatography
The instrument was setup in no time, even without a service engineer on site. Thanks to the disposable pre-columns, carry-over even for complex samples was reduced to a minimum. Great support of the company with regarding to new methods.
Review Date: 15 Jul 2021 | Evosep
How did we do nanoLC before?
Proteomics
The easiest nano/microLC system on the market. Fantastic throughput, very robust and reproducible while maintaining really good performance.
Review Date: 18 Jun 2021 | Evosep
INTEGRATED PURIFICATION AND SEPARATION DELIVERED BY THE EVOSEP ONE
The Evosep One is a standardized platform designed for robustness and high throughput. This is achieved by using Evotips as disposable trap columns, where samples are loaded and desalted offline. The autosampler picks up the tip and integrates elution with liquid chromatography. This removes sample handling steps and reduces injection cycle overheads.
Minimal wear and tear on mechanical components is ensured as all elution and gradient formation happen at low pressure. The Evotip is left for disposal after each run, which then allows partial elution to extend column lifetime. Analytically important peptides are effectively retained, and cross-contamination reduced.
