CORTECS premier columns
Reproducible speed for all your high throughput analysis
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CORTECS premier columns combine the benefits of solid-core particle technology and MaxPeak High Performance Surfaces (HPS). Solid-core particles provide increased column efficiency at low backpressures when compared to fully porous particles of equivalent sizes, and MaxPeak HPS technology mitigates unwanted interactions between analytes and metal ions found within typical stainless-steel columns.
The convenient and efficient combination of these two technologies in one column family provides users with reliable data for all analytes at higher throughput. Ideal for both small molecule and biomolecule LC-MS analysis. CORTECS Premier Columns are available in a broad range of chemistries and in two particles sizes: the CORTECS Premier 2.7 µm Columns for rapid analytical HPLC separations, and the CORTECS Premier 1.6 µm Columns for maximum UHPLC separation performance.
Upgrading from fully porous to solid-core particle columns
Columns packed with solid-core particles deliver sharper peaks and faster separations than those packed with fully porous particles. Discover what Waters solid-core columns can do for your lab, and learn how to choose the particle size option that best suits your lab and delivers the desired results within your system's capabilities.
Improving the analysis of betamethasone and phosphate, acetate, and dipropionate derivatives using CORTECS Premier C8 Columns
Newer column technologies can significantly enhance analytical performance. Discover how the analysis of betamethasone and its phosphate, acetate, and dipropionate derivatives can be improved using CORTECS™ Premier C8 Columns with MaxPeak™ High-Performance Surfaces (HPS) Technology. The inert hardware eliminates interactions with metal surfaces, enhancing peak area, shape, and symmetry, particularly for betamethasone phosphate, while maintaining excellent results for the other analytes.
HPLC separation of bile acids using a CORTECS Premier Phenyl Column
Bile acids play a key role in fat metabolism, yet their accurate measurement is challenging due to isobaric species that require high‑quality chromatographic separation. Researchers need reliable methods that resolve these closely related compounds to support health monitoring and analytical workflows.
Discover how the CORTECS™ Premier Phenyl Column improves separation efficiency, reduces analyte–hardware interactions, and delivers clear resolution of isobaric bile acids, helping scientists generate more confident, reliable LC‑MS data.
