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Captiva ND and ND Lipids

Fully automatable protein precipitation

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Agilent Technologies

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Average Rating 5.0

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Very efficient.

 

Average Rating 5.0

Application Area:

Pesticide residue

Very efficient clean-up product. Works very well with water analysis.

Review Date: 26 Mar 2019 | Agilent Technologies

Fully automatable protein precipitation

Captiva ND plates are a simple to use filtration device designed for the high throughput, automated, in-well protein precipitation. Built with a unique nondrip (ND) membrane, Captiva ND plates allow for solvent first protein precipitation using methanol or acetonitrile. Acidified acetonitrile or methanol help improve recovery for compounds that are stable at acidic pH. The unique dual-filter design delivers fast, uniform flow to avoid filter plugging and ensure reliable filtrate recovery. In addition, Captiva ND Lipid plates are designed to effectively remove phospholipids from biofluids. Ion suppression is significantly reduced for enhanced sensitivity and precision during trace analysis. The depletion of lipid compounds also results in better peak shapes and more reproducible retention times. Captiva ND plates ensure high sample throughput and help to reduce instrumentation downtime in the laboratory, with virtually no need for method development for a wide range of analytes.

Features:

  • Fully automatable protein precipitation
  • Reduced costs and increased productivity due to less instrument downtime
  • Simple and easy-to-use nondrip protein precipitation plate
  • Resists organic solvent flow until vacuum is applied, allowing for streamlined, fully automatable workflow
  • Dual depth filter design allows for fast uniform treatment of samples while avoiding membrane plugging or lost samples
  • In-well filter design removes proteins as efficiently as centrifugation while avoiding additional handling steps and accidental pellet transfer

For Research Use Only. Not for use in diagnostic procedures.

Application NoteSeparations

Filtration makes all the difference

Filtering samples before analysis can help you achieve longer column life, maximize uptime, improve sample integrity, and maximize instrument performance.

In this application note, explore the Agilent Captiva sample preparation filtration portfolio and learn more about how Agilent’s filtration solutions can help to enhance your analyses, from chromatography and mass spectrometry to protein precipitation.


Application NoteSeparations

A Fast Sample Preparation Workflow for Veterinary Drugs Analysis in Salmon

In this application note, Agilent outlines a simple, fast, and robust sample preparation workflow and analytical method that was developed for the analysis of seven classes of 53 widely-used veterinary drugs in salmon. A one-step solvent extraction followed by pass-through cleanup with Agilent Captiva EMR—Lipid was used for the analysis.

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