BIOSTAT® D-DCU
The BIOSTAT® D-DCU is a compact, bioprocess system available for microbial and cell culture applications with working volumes from 10 to 200L. The BIOSTAT D-DCU incorporates many desirable and advanced features to fulfil virtually any demand for modern bioprocess application, such as: Automatic Sterilization in Place (SIP) and Cleaning in Place (CIP), Dual pH and DO measurement capability, Lid lifting device, WIT-Ready filter…
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The BIOSTAT® D-DCU is a compact, bioprocess system available for microbial and cell culture applications with working volumes from 10 to 200L.
The BIOSTAT D-DCU incorporates many desirable and advanced features to fulfil virtually any demand for modern bioprocess application, such as: Automatic Sterilization in Place (SIP) and Cleaning in Place (CIP), Dual pH and DO measurement capability, Lid lifting device, WIT-Ready filter housings, Dual exhaust filter housing line, Tube and shell exhaust cooler, exhaust heater, automatic or manual addition arrays as well as other accessories. Furthermore the BIOSTAT D-DCU is designed to interface Single use storage bags for media addition and harvest as well as single use sampling systems. Due to the modular approach, resulting in various configurations; from baseline to fully-featured, the system offers an excellent solution for every budget and every need.
Features:
- Single or Twin configuration
- 10L, 20L, 30L, 50L, 100L, and 200L working volume
- For microbial or cell culture applications
- Automated Sterilization in Place (SIP)
- Automated Cleaning In Place (CIP)
- Space saving design
- Full qualification support
High-Cell-Density Cultivation of Escherichia coli in a BIOSTAT® D-DCU 10-3 Stainless Steel Bioreactor
Generally, stainless steel bioreactor systems are used for microbial fermentations because their design principles are well known. Consequently, there is a lot of experience and knowledge for these bioreactors resulting in their use over several decades. Furthermore, such bioreactors are available in a scalable range from laboratory to production scale, which enables easy process transfer and scale-up. BIOSTAT® D-DCU is a bioreactor for both microbial and cell culture applications, offering the capability of sterilization in place (SIP). This application note demonstrates the high-cell-density cultivation of Escherichia coli in a BIOSTAT® D-DCU 10-3 Bioreactor.
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