ÄKTA ready™ 450 single-use chromatography system
The ÄKTA ready™ 450 chromatography system is single use and has a low flow rate and hold-up volume for efficient purification of small quantities in a GMP environment.
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ÄKTA ready™ 450 is a single-use liquid chromatography system
designed for small-scale manufacturing. To meet the needs
of purifying small drug volumes, the system has a low flow range of
5 to 450 mL/min per pump and a low hold-up volume. The single-use
flow path minimizes the need for cleaning and cleaning validation,
allowing for quick changeover between productions and reducing
the risk of carryover. The ÄKTA ready™ 450 chromatography system
offers the performance and documentation required for use in a
GMP-regulated environment.
Designed for small-scale manufacturing:
- Small hold-up volume and flow rate support efficient
- purification of small drug volumes.
- Single-use flow path with a fully closed option reduce
- contamination risk.
- Small benchtop footprint makes efficient use of valuable
- facility space.
Testa Challenge 2024 – Accelerate the industrialization of new technology
In this application note from Cytiva, explore the Testa Challenge, an open innovation arena, dedicated to companies in the Technology/Digital/Data/IT sector internationally, to test and verify their technology in a fully funded industry standard bioproduction at Testa Center, Uppsala, Sweden. The provided bioprocess, which is a bioproduction workflow for an antibody intermediate for ADC production, together with the facilities and expertise, will allow an early evaluation of whether an innovation is applicable and successful for the bioprocessing industry.
AAV manufacturing workflow: Scalable, flexible, single-use solutions
In this application note, Cytiva offers solutions to address AAV manufacturing challenges comprehensively. The solutions include obtaining stable inducible producer cell lines, choosing between bioreactors suitable for suspension and adherent cells, capturing viral particles using affinity chromatography, and achieving baseline separation of full and empty capsids.
