Editorial Article: Latest advances in protein biology: Special Feature

From ultrafiltration and extraction to glycosylation and imaging, discover the latest technologies, top tips, and best practices for protein biology research

02 Nov 2020


Protein Biology SelectScience special feature 2020

In this new special feature, we pull together an array of top resources to help you stay up to date with the latest technologies and techniques for protein biology research. Learn how to improve your protein extraction yields; discover a method for highly sensitive gel imaging with reduced exposure to toxic materials; find out how glycosylation analysis is being used to inform recombinant protein selection for COVID-19 research; explore top tips and tricks to optimize your sample preparation workflows, and much more!

Application note - SelectScience Protein Biology special feature 2020

Lab ultrafiltration: Tips & tricks to optimize workflows

Discover how Vivaspin® Centrifugal Concentrators can help you effectively perform sample concentration and buffer exchange and learn top tips to improve recovery and speed up your workflows with Sartorius.

 

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Application note - Protein Biology Special Feature 2020

Gel imaging: Reduced toxicity and enhanced sensitivity

Learn how to achieve repeatable and precise imaging analysis with reduced exposure to toxic materials with the UVP GelStudio from Analytik Jena, offering high sensitivity and stability, with enhanced safety.

 

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Application note: Protein Biology Special Feature 2020

Improved extraction: Best practices for protein sample preparation

Download this guide from Bertin Instruments to learn how to achieve improved protein extraction yields from a variety of sample types. Here, two specific protocols using the Precellys Evolution are outlined.

 

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Application note: Bio-Techne Protein Biology Special Feature 2020

Spike protein: Selecting Spike RBD proteins for COVID-19 research

Learn how Bio-Techne uses direct fluorescent glycan labeling (DFGL) to analyze glycosylation of SARS-CoV-2 Spike proteins to help provide guidance on choosing the most suitable recombinant proteins for COVID-19 research.

 

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Interviews with leading scientists:

  • Co-directors of the ELRIG Research and Innovation 2020 meeting, Dr. Darren Cawkill and Dr. Jon Hutchinson, discuss current trends and challenges in protein biology and drug discovery. Read article>>
  • Prof. Christian Griesinger discusses the advantages of using ultra-high field nuclear magnetic resonance spectroscopy to investigate the structure of intrinsically disordered proteins (IDPs). Read article>>
  • Prof. Jane Dyson discusses the importance of IDPs for protein function and emphasizes the benefits of using nuclear magnetic resonance (NMR) for studying these protein mechanisms. Watch interview>>
  • Prof. Steve Hill describes his research on the ligand binding of cell surface GPCR and RTK proteins. Watch interview>>
  • Dr. Mark Soave highlights how Promega’s NanoLuc® Binary Technology split luciferase assay allows his team to examine protein:protein interactions of G protein-coupled receptors (GPCR) and other proteins in response to drug treatments. Watch interview>>
  • Dr. Richard Kay outlines how he uses mass spectrometry to measure gut hormone peptides related to diabetes, the challenges of detecting low-abundant peptides such as insulin and the benefits of performing peptide mass spectrometry over immunoassays. Watch interview>>

Related resources:

  • Meet the gel imaging system designed to improve workflow efficiency and fit just about anywhere. Read article>>
  • The future of drug discovery: Discover how scientists at Medicine Discovery Catapult are using biomarkers to tailor approaches to patient care, in this exclusive interview with Dr. Sally Price. Read article>>
  • For thermo-sensitive molecules such as proteins, sample preparation is a critical step before proceeding to molecular downstream analysis. In this application note, Bertin Instruments highlights the key considerations in protein sample preparation. Download method>>
  • Xing Wang, from Array Bridge, introduces a new technology for protein conformational analysis and explains how it is being used to study immunogenicity correlation. Watch presentation>>

Your recommendations:

Find out what researchers around the world are saying about the products they use! Eric Bankaitis, a research scientist at Powered Research, LLC., shared his opinion of the Precellys Evolution tissue homogenizer by Bertin Instruments.

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