zPREDICTA to join forces with Science Exchange

The partnership will offer unique patient-derived 3D cell culture services to drug development researchers

21 Nov 2019
Arran Tabary-Davies
Microbiologist

Industry news

Science Exchange, a leading marketplace for outsourced R&D, has announced it is working with zPREDICTA to offer online access to its predictive cancer drug development and testing services.

zPREDICTA is a California-based biotechnology company with expertise in creating human, disease-specific tissue microenvironments for testing drug efficacy and safety. Unlike other platforms, zPREDICTA’s patented 3D models utilize proprietary organ-specific extracellular matrix formulations that match the in vivo milieu of the organ of interest.

These models reconstruct both cellular and extracellular compartments of each tissue, which is especially essential for the testing of immuno-oncology agents. The results have been promising. In one ongoing study comparing clinical outcomes with drug potency in zPREDICTA’s 3D culture, patients’ responses in 18 out of 20 cases were predicted correctly.

“Joining forces with Science Exchange gives us the opportunity to help advance more drug development programs through our newly patented, predictive 3D tissue reconstruction technology,” said zPREDICTA’s CEO, Julia Kirshner, Ph.D. “Researchers around the world can now work with us to tackle new challenges in modeling complex disease states, tissues, and tumors.”

“We are excited to team up with zPREDICTA to make its drug development services rapidly available to our pharmaceutical and biopharmaceutical clients,” said Elizabeth Iorns, Ph.D., co-founder and CEO of Science Exchange. “Science Exchange is committed to supporting the most innovative and qualified providers on our marketplace. zPREDICTA met our rigorous standards for quality and compliance while significantly advancing the field of disease modeling through their own research.”

About zPREDICTA

zPREDICTA, founded in 2014 by two Ph.D. scientists, Julia Kirshner and Mukti Parikh on the principle that cures for human diseases require laboratory systems based on human biology.

zPREDICTA, backed by Y Combinator, the premier Bay Area accelerator, is a pioneer in organ-specific and disease-specific 3D cell culture platforms for cancer drug testing. zPREDICTA technology demonstrates high clinical relevance, enabling its pharma clients to manage pipeline attrition more efficiently by identifying drugs that are effective in patients, from the hundreds, and often thousands, of compounds in development.

The mission of zPREDICTA is to eliminate the guesswork from drug development, thus reducing the time and cost of bringing life-saving therapies to market.

About Science Exchange

Science Exchange provides R&D organizations with a rapid path to discovery, development and commercialization.

Science Exchange includes an efficient source-to-secure platform for ordering 6,000+ services from a network of more than 2,500 qualified outsourced research providers, all with pre-established contracts in place that protect client intellectual property and confidentiality.

The platform increases access to innovation and improves productivity, freeing scientists from administrative tasks and delays associated with sourcing, establishing and managing service provider contracts. Additionally, the Science Exchange enterprise program enables large R&D organizations to consolidate research outsourcing spend into a single strategic relationship, driving efficiency, improving transparency and oversight, and delivering cost savings.

Since being founded in 2011, Science Exchange has raised more than $58 million from Norwest Venture Partners, Maverick Capital Ventures, Union Square Ventures, Collaborative Fund, Index Ventures, OATV, the YC Continuity Fund, and others.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.
zPREDICTA to join forces with Science Exchange