Proteona’s ESCAPE™ platform selected for SARS-CoV-2 vaccine characterization

11 May 2020
Edward Carter
Publishing / Media

Industry news

Proteona has announced that it is beginning a partnership with Professor Nikolai Petrovsky from Flinders University to characterize the clinical response to a new SARS-CoV-2 vaccine. Professor Petrovsky, the director of endocrinology at Flinders Medical Centre, will be starting clinical trials of the vaccine soon.

Proteona will use its ESCAPE™ technology to profile the immune response of patients receiving the vaccine. The ESCAPE™ platform provides a deep understanding of the immune cells through single cell proteogenomic profiling. It enables the researchers to identify key aspects of immune activation and then compare back to responses from other vaccination data using Proteona’s proprietary single cell database and AI tools.

Professor Petrovsky commented, “Years of work on vaccines have taught me that there are a lot of potential pitfalls in developing an effective vaccine. It is critical now as we speed through vaccine development for preventing COVID-19 that we gain a deep understanding of how each vaccine is working. We must measure the body’s response as deeply as possible to understand how the entire immune system is reacting and use those data to guide decision making about the vaccine’s efficacy. Our own vaccine will be starting human trials soon and we are happy to be working again with Proteona to deeply profile the vaccine response using their ESCAPE platform.”

The vaccine development is done in collaboration with Vaxine Pty Ltd, a company based in South Australia focusing on development of innovative vaccine technologies. The vaccine is currently undergoing animal testing in the US, before proceeding to human clinical trials.

“This type of work is where we excel and we are happy to play a role now in helping to bring forward vaccines for COVID-19,” said Andreas Schmidt, CEO of Proteona. “The data we collect as part of this study will benefit all vaccine development efforts around the world.”

Proteona noted that it is also in discussion with other vaccine developers to generate a common platform for data analysis across the different SARS-CoV-2 vaccination programs.

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ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Vaccine DevelopmentVaccine development focuses on creating immunizations to protect against infectious diseases. The process involves identifying antigens, developing and testing vaccine efficacy, and ensuring safety through preclinical testing and multiple clinical trial phases. Scientists use various approaches, including weakened or inactivated viruses, protein subunits, or mRNA. Advanced platforms and rapid diagnostic tools aid in vaccine research and testing. Explore vaccine development solutions in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers. CoronavirusCoronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like COVID-19. Research into the biology, transmission, and treatment of coronaviruses has become a global priority, particularly since the emergence of SARS-CoV-2. Understanding the virus�s structure and behavior is essential for developing vaccines, diagnostics, and antiviral treatments. Explore our peer-reviewed product directory to discover the latest research tools, diagnostic tests, vaccines, and treatments for coronavirus, compare products, read reviews, and receive pricing directly from manufacturers.